Pharmacological treatment of chronic heart failure

被引：24
|
作者：
Adorisio, Rachele
De Luca, Leonardo
Rossi, Joseph
Gheorghiade, Mihai
机构：
[1] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA
[2] Bambino Gesu Pediat Hosp, Dept Cardiol & Cardiac Surg, Rome, Italy
[3] European Hosp, Div Cardiol, Rome, Italy
来源：
HEART FAILURE REVIEWS | 2006年 / 11卷 / 02期
关键词：
heart failure; drugs; angiotensin-converting enzyme inhibitors; beta-blockers; diuretics; digitalis;
D O I：
10.1007/s10741-006-9482-z
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Heart failure (HF) is associated with a high morbidity and mortality in the Western World. Our knowledge of the epidemiology, pathophysiology, and therapy has improved dramatically during the last 20 years. Pharmacological treatment, as it stands today, is a combination of preventive and symptomatic strategies. The mainstay life-saving drugs are angiotensin-converting enzyme inhibitors and beta-blockers. Additional benefits are obtained when angiotensin-receptor blockers or aldosterone antagonists are added. Digitalis and/or diuretics are useful for symptom reduction. In addition, combination therapy with hydralazine and isosorbide dinitrate is recommended in African Americans.
引用
收藏
页码：109 / 123
页数：15
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