Towards A Multi-Wavelength Spectroscopy Platform for Blood Characterization and Analysis

Passing multiple light wavelengths through a blood sample makes it possible to investigate the presence and composition of cells, metabolytes and analytes such as blood cells, glucose, lactate and oxygen, providing valuable indications for diagnostic and health monitoring. In this paper, we present a test prototype of a multi-wavelength blood spectroscopy platform integrated with a microfluidic substrate to collect and convey blood samples through a series of micro-LEDs and a photo-detector. This spectroscopy platform is a proof of concept for a system that can collect absorbance and transmittance parameters of blood samples at several wavelengths within the visible and NIR spectrum, and transmit them wirelessly to a base station for real-time calculation and analysis. In-vitro measurements are performed with the proposed prototype with 5 channels covering wavelength from 400 nm to 940 nm. A full characterization results of the proposed device are presented.