Design - a new way to look at old molecules

被引:4
|
作者
Spalvieri, Davide [1 ,2 ]
Mauviel, Anne-Marine [1 ,2 ]
Lambert, Matthieu [3 ]
Ferey, Nicolas [1 ,2 ,4 ]
Sacquin-Mora, Sophie [1 ,2 ]
Chavent, Matthieu [5 ]
Baaden, Marc [1 ,2 ]
机构
[1] Univ Paris Cite, CNRS, Lab Biochim Theor, UPR 9080, 13 Rue Pierre & Marie Curie, F-75005 Paris, France
[2] Fdn Edmond Rothschild, Inst Biol Phys Chim, Paris, France
[3] Ecole Estienne, Paris, France
[4] Univ Paris Saclay, Lab Interdisciplinaire Sci Numer, CNRS, F-91405 Orsay, France
[5] Univ Paul Sabatier, Univ Toulouse, Inst Pharmacol & Biol Struct, CNRS, F-31400 Toulouse, France
关键词
exploded views; illustration; ion channels; molecular design; outreach; VISUALIZATION; ALGORITHM;
D O I
10.1515/jib-2022-0020
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We discuss how design enriches molecular science, particularly structural biology and bioinformatics. We present two use cases, one in academic practice and the other to design for outreach. The first case targets the representation of ion channels and their dynamic properties. In the second, we document a transition process from a research environment to general-purpose designs. Several testimonials from practitioners are given. By describing the design process of abstracted shapes, exploded views of molecular structures, motion-averaged slices, 360-degree panoramic projections, and experiments with lit sphere shading, we document how designers help make scientific data accessible without betraying its meaning, and how a creative mind adds value over purely data-driven visualizations. A similar conclusion was drawn for public outreach, as we found that comic-book-style drawings are better suited for communicating science to a broad audience.
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页数:14
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