Brainstem and limbic encephalitis with paraneoplastic neuromyelitis optica

被引：9
|
作者：
Moussawi, Khaled [1 ,2 ,3 ]
Lin, David J. [1 ,2 ,3 ]
Matiello, Marcelo [1 ,2 ,3 ]
Chew, Sheena [1 ,2 ,3 ]
Morganstern, Daniel [3 ,4 ]
Vaitkevicius, Henrikas [1 ,3 ]
机构：
[1] Brigham & Womens Hosp, Dept Neurol, Boston, MA 02115 USA
[2] Massachusetts Gen Hosp, Dept Neurol, Wang Ambulatory Care Ctr, Boston, MA 02114 USA
[3] Harvard Univ, Sch Med, Boston, MA USA
[4] Dana Farber Canc Inst, Boston, MA 02115 USA
来源：
JOURNAL OF CLINICAL NEUROSCIENCE | 2016年 / 23卷
关键词：
Brainstem encephalitis; Breast cancer; Limbic encephalitis; Neuromyelitis optica; Neuromyelitis optica spectrum disorders; Paraneoplastic syndrome; EXTENSIVE TRANSVERSE MYELITIS; AQUAPORIN-4; ANTIBODY; CANCER;
D O I：
10.1016/j.jocn.2015.08.006
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The spectrum of disorders associated with anti-neuromyelitis optica (NMO) antibody is being extended to include infrequent instances associated with cancer. We describe a patient with brainstem and limbic encephalitis from NMO-immunoglobulin G in serum and cerebrospinal fluid in the context of newly diagnosed breast cancer. The neurological features markedly improved with excision of her breast cancer and immune suppressive therapy. This case further broadens the NMO spectrum disorders (NMOSD) by an association between NMOSD and cancer and raises the question of coincidental occurrence and the appropriate circumstances to search for a tumor in certain instances of NMO. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码：159 / 161
页数：3
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