Personalized Therapy Approach for Hospitalized Patients with Coronavirus Disease 2019

被引：29

作者：

Garcia-Vidal, Carolina ^{[1
]}

Moreno-Garcia, Estela ^{[1
]}

Hernandez-Meneses, Marta ^{[1
]}

Puerta-Alcalde, Pedro ^{[1
]}

Chumbita, Mariana ^{[1
]}

Garcia-Pouton, Nicole ^{[1
]}

Linares, Laura ^{[1
]}

Rico, Veronica ^{[1
]}

Cardozo, Celia ^{[1
]}

Antonio Martinez, Jose ^{[1
]}

Garcia, Felipe ^{[1
]}

Mensa, Josep ^{[1
]}

Castro, Pedro ^{[2
]}

Maria Nicolas, Jose ^{[2
]}

Munoz, Jose ^{[3
]}

Vidal, David ^{[4
]}

Soriano, Alex ^{[1
]}

机构：

[1] Hosp Clin Barcelona, Dept Infect Dis, C Villarroel 110, Barcelona 08036, Spain

[2] Barcelona Univ, Hosp Clin, IDIBAPS, Med Intens Care Unit, Barcelona, Spain

[3] Univ Barcelona, Hosp Clin, ISGLOBAL, Ctr Res Int Hlth CRESIB, Barcelona, Spain

[4] Hosp Clin Barcelona, Comp Syst Unit, Barcelona, Spain

来源：

CLINICAL INFECTIOUS DISEASES | 2022年 / 74卷 / 01期

基金：

欧盟地平线“2020”;

关键词：

COVID-19; personalized therapy; pneumonia; patterns;

D O I：

10.1093/cid/ciaa964

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Hospitalized patients with coronavirus disease 2019 (COVID-19) experiencing respiratory symptoms have different complications (inflammatory, co-infection, and thrombotic) that are identifiable by analytics patterns. Personalized treatment decisions decreased early mortality (odds ratio [OR] .144; 95% confidence interval [CI] .03-.686; P=.015). Increasing age (OR 1.06; P=.038) and therapeutic effort limitation (OR 9.684; P<.001) were associated with higher mortality.

引用

页码：127 / 132

页数：6

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