Analysis-ready datasets for insecticide resistance phenotype and genotype frequency in African malaria vectors

被引:22
|
作者
Moyes, Catherine L. [1 ]
Wiebe, Antoinette [1 ]
Gleave, Katherine [2 ]
Trett, Anna [2 ]
Hancock, Penelope A. [1 ]
Padonou, Germain Gil [3 ]
Chouaibou, Mouhamadou S. [4 ]
Sovi, Arthur [3 ,5 ]
Buelmaali, Sara A. A. [6 ]
Ochomo, Eric [7 ]
Ntonio-Nkondjio, Christophe A. [8 ]
Dengela, Dereje [9 ]
Kawada, Hitoshi [10 ]
Dabire, Roch K. [11 ]
Donnelly, Martin J. [2 ]
Mbogo, Charles [12 ,13 ]
Fornadel, Christen [14 ]
Coleman, Michael [2 ]
机构
[1] Univ Oxford, Li Ka Shing Ctr Hlth Informat & Discovery, Big Data Inst, Oxford OX1 7LF, England
[2] Univ Liverpool Liverpool Sch Trop Med, Dept Vector Biol, Liverpool L1, Merseyside, England
[3] CREC, 06BP2604, Cotonou, Benin
[4] Ctr Suisse Rech Sci Cote Ivoire, 01BP1303,Abj 01, Abidjan, Cote Ivoire
[5] Univ Parakou, Fac Agron, BP123, Parakou, Benin
[6] Fed Minist Hlth, Dept Med Entomol, Natl Publ Hlth Lab, Khartoum, Sudan
[7] Ctr Global Hlth Res, Kenya Med Res Inst, Kisumu, Kenya
[8] Org Coordinat Lutte Endemies Afrique Cent OCEAC, Lab Rech Paludisme, POB 288, Yaounde, Cameroon
[9] Abt Associates Inc, US PMI VectorLink Project, 6130 Execut Blvd, Rockville, MD 20852 USA
[10] Nagasaki Univ, Inst Trop Med, Dept Vector Ecol & Environm, Nagasaki, Japan
[11] Inst Rech Sci Sante, Dept Med Biol & Publ Hlth, Bobo Dioulasso, Burkina Faso
[12] KEMRI Ctr Geog Med Res Coast, POB 230, Kilifi 80108, Kenya
[13] KEMRI Wellcome Trust Res Program, POB 43640, Nairobi 00100, Kenya
[14] US Agcy Int Dev, US Presidents Malaria Initiat, Washington, DC 20523 USA
基金
比尔及梅琳达.盖茨基金会; 英国惠康基金;
关键词
D O I
10.1038/s41597-019-0134-2
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The impact of insecticide resistance in malaria vectors is poorly understood and quantified. Here a series of geospatial datasets for insecticide resistance in malaria vectors are provided, so that trends in resistance in time and space can be quantified, and the impact of resistance found in wild populations on malaria transmission in Africa can be assessed. Specifically, data have been collated and geopositioned for the prevalence of insecticide resistance, as measured by standard bioassays, in representative samples of individual species or species complexes. Data are provided for the Anopheles gambiae species complex, the Anopheles funestus subgroup, and for nine individual vector species. Data are also given for common genetic markers of resistance to support analyses of whether these markers can improve the ability to monitor resistance in low resource settings. Allele frequencies for known resistance-associated markers in the Voltage-gated sodium channel (Vgsc) are provided. In total, eight analysis-ready, standardised, geopositioned datasets encompassing over 20,000 African mosquito collections between 1957 and 2017 are released.
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页数:11
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