2-methoxy-10,11-dihydro-5H-dibenzo[a,d]cycloheplen-5-one:: Application for the peptide amide linkers and guanidino protection of arginine during Fmoc solid-phase peptide synthesis

The synthesis of the biologically important hormones and neurotransmitters incorporating the C-terminal peptide amide by SPPS would attract much attention for biochemical and pharmaceutical research and production. Accordingly, the design and development of the C-terminal peptide amide linkers as a carboxy-terminus linkage have much potential for peptide synthesis.