Background. It has been suggested that preoperative biliary drainage increases the risk of infectious complications of pancreaticoduodenectomy. Aims. The aim of this study was to assess complications related to biliary stents/drains and postoperative morbidity in patients undergoing neoadjuvant chemoradiotherapy for periampullary cancer. Patients. One hundred and eighty-four patients with periampullary neoplasms were prospectively selected for neoadjuvant external beam radiation therapy and 5-fluorouracil-based chemotherapy between 1995 and 2002. Methods. The data were retrospectively completed and analysed with respect to biliary drainage, efficacy and complications of endoscopic biliary stents and postoperative morbidity. Patients who had undergone a surgical biliary bypass were excluded. Results. Data were completed in 168 patients. One hundred and nineteen patients were treated with endoscopic biliary stents, 18 patients had a percutaneous biliary drain and 31 patients did not require biliary drainage. Hospitalisation for stent-related complications was necessary in 15% of the patients with endoscopic biliary stents. Seventy-two patients underwent pancreaticoduodenectomy. There was no significant difference in the rate of wound infections, intra-abdominal abscesses and overall complications between the groups with and without preoperative biliary drainage. Conclusions. Postoperative infectious complications are common in patients both with and without preoperative biliary drainage. A statistically significant difference in complication rates was not observed between these groups. (C) 2004 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
机构:
Rouen Univ Hosp, Dept Digest Surg, 1 Rue Germont, F-76031 Rouen, FranceRouen Univ Hosp, Dept Digest Surg, 1 Rue Germont, F-76031 Rouen, France
Tortajada, Pauline
Sauvanet, Alain
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Hop Beaujon, Dept Hepatobiliary & Liver Transplantat, 100 Blvd Gen Leclerc, F-92118 Clichy, FranceRouen Univ Hosp, Dept Digest Surg, 1 Rue Germont, F-76031 Rouen, France
Sauvanet, Alain
Truant, Stephanie
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Hop Huriez, Dept Digest Surg & Transplantat, Rue Michel Polonowski, F-59037 Lille, FranceRouen Univ Hosp, Dept Digest Surg, 1 Rue Germont, F-76031 Rouen, France
机构:
CHU Kremlin Bicetre, Dept Digest Surg, 78 Rue Gen Leclerc, F-94270 Le Kremlin Bicetre, FranceRouen Univ Hosp, Dept Digest Surg, 1 Rue Germont, F-76031 Rouen, France
Benoist, Stephane
Muscari, Fabrice
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CHU Toulouse Rangueil, Dept Digest Surg & Transplantat, 1 Ave Pr Jean Poulhes, F-31059 Toulouse, FranceRouen Univ Hosp, Dept Digest Surg, 1 Rue Germont, F-76031 Rouen, France
Muscari, Fabrice
Regimbeau, Jean Marc
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CHU Amiens Picardie Site Sud, Dept Digest Surg, 1 Rond Point Prof Christian Cabrol, F-80054 Amiens 1, FranceRouen Univ Hosp, Dept Digest Surg, 1 Rue Germont, F-76031 Rouen, France
Regimbeau, Jean Marc
Gaujoux, Sebastien
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Hop Cochin, Dept Digest Surg Hepatobiliary & Metab Surg, 27 Rue Faubourg, F-75014 Paris, FranceRouen Univ Hosp, Dept Digest Surg, 1 Rue Germont, F-76031 Rouen, France
Gaujoux, Sebastien
Cunha, Antonio Sa
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Ctr Hepatobiliaire Paul Brousse, Dept Hepatobiliary & Liver Transplantat, 38 Rue Chapelle, F-94800 Villejuif, FranceRouen Univ Hosp, Dept Digest Surg, 1 Rue Germont, F-76031 Rouen, France
Cunha, Antonio Sa
Schwarz, Lillian
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Rouen Univ Hosp, Dept Digest Surg, 1 Rue Germont, F-76031 Rouen, FranceRouen Univ Hosp, Dept Digest Surg, 1 Rue Germont, F-76031 Rouen, France
机构:
Hosp Casa Sollievo Sofferenza, IRCCS, Dept Surg, San Giovanni Rotondo, ItalyHosp Casa Sollievo Sofferenza, IRCCS, Dept Surg, San Giovanni Rotondo, Italy
di Mola, F. F.
Tavano, F.
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Hosp Casa Sollievo Sofferenza, IRCCS, Dept Surg, San Giovanni Rotondo, ItalyHosp Casa Sollievo Sofferenza, IRCCS, Dept Surg, San Giovanni Rotondo, Italy
Tavano, F.
De Bonis, A.
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Hosp Casa Sollievo Sofferenza, IRCCS, Dept Surg, San Giovanni Rotondo, ItalyHosp Casa Sollievo Sofferenza, IRCCS, Dept Surg, San Giovanni Rotondo, Italy
De Bonis, A.
Grottola, T.
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Hosp Casa Sollievo Sofferenza, IRCCS, Dept Surg, San Giovanni Rotondo, ItalyHosp Casa Sollievo Sofferenza, IRCCS, Dept Surg, San Giovanni Rotondo, Italy
Grottola, T.
Tardio, M.
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Hosp Casa Sollievo Sofferenza, IRCCS, Dept Surg, San Giovanni Rotondo, ItalyHosp Casa Sollievo Sofferenza, IRCCS, Dept Surg, San Giovanni Rotondo, Italy
Tardio, M.
Valvano, M. R.
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Hosp Casa Sollievo Sofferenza, IRCCS, Unit Gastroenterol, San Giovanni Rotondo, ItalyHosp Casa Sollievo Sofferenza, IRCCS, Dept Surg, San Giovanni Rotondo, Italy
Valvano, M. R.
Andriulli, A.
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Hosp Casa Sollievo Sofferenza, IRCCS, Unit Gastroenterol, San Giovanni Rotondo, ItalyHosp Casa Sollievo Sofferenza, IRCCS, Dept Surg, San Giovanni Rotondo, Italy
Andriulli, A.
di Sebastiano, P.
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Hosp Casa Sollievo Sofferenza, IRCCS, Dept Surg, San Giovanni Rotondo, ItalyHosp Casa Sollievo Sofferenza, IRCCS, Dept Surg, San Giovanni Rotondo, Italy
机构:
Chinese Peoples Liberat Army Gen Hosp, Dept & Inst Hepatobiliary Surg, Beijing 100853, Peoples R China
Nankai Univ, Sch Med, Tianjin 300071, Peoples R ChinaChinese Peoples Liberat Army Gen Hosp, Dept & Inst Hepatobiliary Surg, Beijing 100853, Peoples R China
Huang, Xin
Liang, Bin
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Chinese Peoples Liberat Army Gen Hosp, Dept & Inst Hepatobiliary Surg, Beijing 100853, Peoples R ChinaChinese Peoples Liberat Army Gen Hosp, Dept & Inst Hepatobiliary Surg, Beijing 100853, Peoples R China
Liang, Bin
Zhao, Xiang-Qian
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Chinese Peoples Liberat Army Gen Hosp, Dept & Inst Hepatobiliary Surg, Beijing 100853, Peoples R ChinaChinese Peoples Liberat Army Gen Hosp, Dept & Inst Hepatobiliary Surg, Beijing 100853, Peoples R China
Zhao, Xiang-Qian
Zhang, Fu-Bo
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Chinese Peoples Liberat Army Gen Hosp, Dept & Inst Hepatobiliary Surg, Beijing 100853, Peoples R China
Nankai Univ, Sch Med, Tianjin 300071, Peoples R ChinaChinese Peoples Liberat Army Gen Hosp, Dept & Inst Hepatobiliary Surg, Beijing 100853, Peoples R China
Zhang, Fu-Bo
Wang, Xi-Tao
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Chinese Peoples Liberat Army Gen Hosp, Dept & Inst Hepatobiliary Surg, Beijing 100853, Peoples R China
Nankai Univ, Sch Med, Tianjin 300071, Peoples R ChinaChinese Peoples Liberat Army Gen Hosp, Dept & Inst Hepatobiliary Surg, Beijing 100853, Peoples R China
Wang, Xi-Tao
Dong, Jia-Hong
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Chinese Peoples Liberat Army Gen Hosp, Dept & Inst Hepatobiliary Surg, Beijing 100853, Peoples R ChinaChinese Peoples Liberat Army Gen Hosp, Dept & Inst Hepatobiliary Surg, Beijing 100853, Peoples R China