Impact of allergen immunotherapy in allergic asthma

被引：32

作者：

Zhang, Wenming ^{[1
]}

Lin, Chunrong ^{[1
]}

Sampath, Vanitha ^{[1
]}

Nadeau, Kari ^{[1
]}

机构：

[1] Stanford Univ, Sean N Parker Ctr Allergy & Asthma Res, Stanford, CA 94305 USA

来源：

IMMUNOTHERAPY | 2018年 / 10卷 / 07期

关键词：

allergen immunotherapy (AIT); allergic asthma; mechanisms; omalizumab; subcutaneous immunotherapy (SCIT); sublingual immunotherapy (SLIT); MITE SUBLINGUAL IMMUNOTHERAPY; GRASS-POLLEN IMMUNOTHERAPY; INTERNATIONAL CONSENSUS; DOUBLE-BLIND; RESPIRATORY ALLERGY; CLINICAL-EFFICACY; IMMUNOGLOBULIN-E; FOLLOW-UP; CHILDREN; SAFETY;

D O I：

10.2217/imt-2017-0138

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Although traditional pharmacological approaches improve outcomes in disease management for allergic asthma, these fail to modify the underlying immune responses. Allergen immunotherapy remains the only etiological therapy for the treatment of respiratory allergies for which clinical efficacy has been demonstrated through several well-controlled studies. In this review, we examine evidence from the past 5 years regarding the impact of allergen immunotherapy on allergic asthma to inform practitioners and stimulate further discussion and research.

引用

页码：579 / 593

页数：15

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