Concise enantioselective synthesis of abscisic acid and a new analogue

被引：26

作者：

Smith, Timothy R. ^{[1
]}

Clark, Andrew J. ^{[1
]}

Clarkson, Guy J. ^{[1
]}

Taylor, Paul C. ^{[1
]}

Marsh, Andrew ^{[1
]}

机构：

[1] Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2006年 / 4卷 / 22期

关键词：

D O I：

10.1039/b611880a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Short and high-yielding syntheses of enantiomerically pure (S)-(+) and (R)-(-)- abscisic acid are described. The syntheses proceed through key intermediates that preferentially recrystallise as single diastereoisomers for each enantiomer. This route allows the preparation of either enantiomer of abscisic acid in ca. 30% overall yield, and as demonstrated, gives access to an enantiomerically pure abscisic acid analogue.

引用

页码：4186 / 4192

页数：7

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