Neonatal stroke: a review of the current evidence on epidemiology, pathogenesis, diagnostics and therapeutic options

被引:42
|
作者
van der Aa, N. E. [1 ]
Benders, M. J. N. L. [1 ]
Groenendaal, F. [1 ]
de Vries, L. S. [1 ]
机构
[1] UMC Utrecht, Wilhelmina Childrens Hosp, Dept Neonatol, NL-3508 AB Utrecht, Netherlands
关键词
Cerebral sinovenous thrombosis; MRI; Neonatal stroke; ARTERIAL ISCHEMIC-STROKE; CEREBRAL SINOVENOUS THROMBOSIS; PERINATAL STROKE; THALAMIC HEMORRHAGE; TERM INFANTS; RISK-FACTORS; CHILDREN; INFARCTION; PREDICTION; DISORDERS;
D O I
10.1111/apa.12555
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Neonatal stroke, including perinatal arterial ischaemic stroke and cerebral sinovenous thrombosis, remains a serious problem in the neonate. This article reviews the current evidence on epidemiology, pathogenesis, diagnostics and therapeutic options. ConclusionAlthough our understanding of the underlying mechanisms and possible risk factors has improved, little progress has been made towards therapeutic options. Considering the high incidence of neurological sequelae, the need for therapeutic options is high and should be the focus of future research.
引用
收藏
页码:356 / 364
页数:9
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