Dietary fatty acids affecting hepatic metabolism and atherosclerosis - mechanisms unravelled using a proteomics approach

被引:1
|
作者
Rodriguez Gutierrez, Guillermo [1 ]
de Roos, Baukje [1 ]
机构
[1] Rowett Res Inst, Div Vasc Hlth, Aberdeen AB21 9SB, Scotland
关键词
Atherosclerosis; Dietary fatty acids; Extra virgin olive oils; Hepatic lipid metabolism; Proteomics; CONJUGATED LINOLEIC-ACID; EARLY AORTIC ATHEROSCLEROSIS; MEDITERRANEAN DIET; FISH CONSUMPTION; SERUM-LIPIDS; NUTRITION; LIVER; RISK; MICE; OIL;
D O I
10.3989/gya.086308
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Dietary fatty acids play an important role in the aetiology of coronary heart disease. The effects of dietary fatty acids on lipoprotein metabolism are well. described, but additional or alternative mechanisms relating to potential influence on coronary heart disease are not known. This review describes how proteomics techniques have been used to identify proteins that are differentially regulated by dietary fatty acids. Such proteins may reveal pathways by which dietary fatty acids influence disease risk.
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页码:28 / 32
页数:5
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