According to the present guidelines, patients with coronary stents are to be treated with dual antiplatelet therapy. In case surgery is needed, the risk of a fatal stent thrombosis by withdrawing antithrombotics needs to be balanced in each individual case against the risk of haemorrhagic complications on continued antiplatelet medication. We present a case of fatal stent thrombosis and discuss the current evidence regarding perioperative continuation and interruption of antiplatelet therapy for this patient population. In summary the haemorrhagic risk with acetylsalicylic acid for secondary prevention seems very low, and it should be discontinued only in selected cases. Continued dual anticoagulation concepts are also discussed.
机构:
Technion Israel Inst Technol, Rambam Med Ctr, Dept Cardiol, Bruce Rappaport Fac Med, IL-31096 Haifa, IsraelTechnion Israel Inst Technol, Rambam Med Ctr, Dept Cardiol, Bruce Rappaport Fac Med, IL-31096 Haifa, Israel
Cohen, Eran
Osherov, Azriel B.
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Technion Israel Inst Technol, Rambam Med Ctr, Dept Cardiol, Bruce Rappaport Fac Med, IL-31096 Haifa, IsraelTechnion Israel Inst Technol, Rambam Med Ctr, Dept Cardiol, Bruce Rappaport Fac Med, IL-31096 Haifa, Israel
Osherov, Azriel B.
Edry, Ruth
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Technion Israel Inst Technol, Rambam Med Ctr, Dept Anesthesiol, Bruce Rappaport Fac Med, IL-31096 Haifa, IsraelTechnion Israel Inst Technol, Rambam Med Ctr, Dept Cardiol, Bruce Rappaport Fac Med, IL-31096 Haifa, Israel
Edry, Ruth
Sebbag, Anat
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Technion Israel Inst Technol, Rambam Med Ctr, Dept Cardiol, Bruce Rappaport Fac Med, IL-31096 Haifa, IsraelTechnion Israel Inst Technol, Rambam Med Ctr, Dept Cardiol, Bruce Rappaport Fac Med, IL-31096 Haifa, Israel
Sebbag, Anat
Massalha, Samia
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Technion Israel Inst Technol, Rambam Med Ctr, Dept Cardiol, Bruce Rappaport Fac Med, IL-31096 Haifa, IsraelTechnion Israel Inst Technol, Rambam Med Ctr, Dept Cardiol, Bruce Rappaport Fac Med, IL-31096 Haifa, Israel
Massalha, Samia
Kerner, Arthur
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Technion Israel Inst Technol, Rambam Med Ctr, Dept Cardiol, Bruce Rappaport Fac Med, IL-31096 Haifa, IsraelTechnion Israel Inst Technol, Rambam Med Ctr, Dept Cardiol, Bruce Rappaport Fac Med, IL-31096 Haifa, Israel
Kerner, Arthur
Roguin, Ariel
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Technion Israel Inst Technol, Rambam Med Ctr, Dept Cardiol, Bruce Rappaport Fac Med, IL-31096 Haifa, IsraelTechnion Israel Inst Technol, Rambam Med Ctr, Dept Cardiol, Bruce Rappaport Fac Med, IL-31096 Haifa, Israel
机构:
Univ London St Georges Hosp, St Georges Sch Anaesthesia, London SW17 0QT, EnglandUniv London St Georges Hosp, St Georges Sch Anaesthesia, London SW17 0QT, England
Jones, Chris
Liban, Bernard
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Univ London St Georges Hosp, St Georges Sch Anaesthesia, London SW17 0QT, EnglandUniv London St Georges Hosp, St Georges Sch Anaesthesia, London SW17 0QT, England
机构:
Ohio State Univ, Med Ctr, Dept Anesthesiol, Doan Hall N411 410 10th Ave, Columbus, OH 43210 USAOhio State Univ, Med Ctr, Dept Anesthesiol, Doan Hall N411 410 10th Ave, Columbus, OH 43210 USA
Dimitrova, G.
Tulman, D. B.
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Ohio State Univ, Med Ctr, Dept Anesthesiol, Doan Hall N411 410 10th Ave, Columbus, OH 43210 USAOhio State Univ, Med Ctr, Dept Anesthesiol, Doan Hall N411 410 10th Ave, Columbus, OH 43210 USA
Tulman, D. B.
Bergese, S. D.
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Ohio State Univ, Med Ctr, Dept Anesthesiol, Doan Hall N411 410 10th Ave, Columbus, OH 43210 USA
Ohio State Univ, Med Ctr, Dept Neurosurg, Columbus, OH 43210 USAOhio State Univ, Med Ctr, Dept Anesthesiol, Doan Hall N411 410 10th Ave, Columbus, OH 43210 USA