Influence of γ irradiation on the mechanical strength and in vitro biodegradation of porous hydroxyapatite/collagen composite

被引：12

作者：

Yunoki, Shunji

Ikoma, Toshiyuki ^{[1
]}

Monkawa, Akira

Ohta, Kazushi

Tanaka, Junzo

Sotome, Shinichi

Shinomiya, Kenichi

机构：

[1] Natl Inst Mat Sci, Ctr Biomat, Tsukuba, Ibaraki 3050044, Japan

[2] Tokyo Med & Dent Univ, Dept Orthoped Surg, Tokyo 1138510, Japan

来源：

JOURNAL OF THE AMERICAN CERAMIC SOCIETY | 2006年 / 89卷 / 09期

关键词：

D O I：

10.1111/j.1551-2916.2006.01151.x

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Gamma irradiation treatment (GIT) is the most widely used sterilization method for biomaterials in spite of the potential to degrade polymers. The adverse effects of GIT on the mechanical properties and biological stabilities of porous hydroxyapatite/collagen (HAp/Col) composites were investigated in this study. Those properties of a porous HAp/Col composite stabilized by dehydrothermal treatment (DHT) drastically decreased by GIT in the same manner as conventional pure Col materials. DHT after GIT could partially eliminate the adverse effects, due to the introduction of cross-linkage among the degraded Col molecules.

引用

页码：2977 / 2979

页数：3

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