Total synthesis of nortopsentins A-D, marine alkaloids

被引:0
|
作者
Kawasaki, I [1 ]
Yamashita, M [1 ]
Ohta, S [1 ]
机构
[1] KYOTO PHARMACEUT UNIV, YAMASHIMA KU, KYOTO 607, JAPAN
关键词
imidazole; marine alkaloid; Suzuki reaction; palladium catalyst; arylboronic acid; nortopsentin;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Nortopsentins A-D, antifungal 1,4-bisindolylimidazole marine alkaloids isolated from a sponge, were synthesized through palladium-catalyzed cross-coupling of 3-indolylboronic and 6-bromo-3-indolylboronic acids with halogenoimidazoles as the key reaction.
引用
收藏
页码:1831 / 1839
页数:9
相关论文
共 50 条
  • [1] Total synthesis of natural alkaloids Schwarzinicines A-D
    Annapurna, K.
    Narsaiah, A. Venkat
    TETRAHEDRON, 2024, 155
  • [2] Total synthesis of the marine cytotoxic caulibugulones A-D
    Alagille, D
    Baldwin, RM
    Tamagnan, GD
    TETRAHEDRON LETTERS, 2004, 45 (32) : 6179 - 6181
  • [3] Total synthesis of the marine alkaloids Caulibugulones A and D
    Prakash, K. S.
    Nagarajan, Rajagopal
    TETRAHEDRON, 2015, 71 (05) : 801 - 804
  • [4] An efficient synthesis method targeted to marine alkaloids marinacarbolines A-D and their antitumor activities
    Li, Jun
    Tang, Yang
    Jin, Hui-Juan
    Cui, Yi-Di
    Zhang, Li-Juan
    Jiang, Tao
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2015, 17 (03) : 299 - 305
  • [5] Total synthesis of zyzzyanones A-D
    Nadkarni, Dwayaja H.
    Murugesan, Srinivasan
    Velu, Sadanandan E.
    TETRAHEDRON, 2013, 69 (20) : 4105 - 4113
  • [6] Total Synthesis of Ramonanins A-D
    Harvey, Ross S.
    Mackay, Emily G.
    Roger, Lukas
    Paddon-Row, Michael N.
    Sherburn, Michael S.
    Lawrence, Andrew L.
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 54 (06) : 1795 - 1798
  • [7] Total synthesis of gibbilimbols A-D
    Vyvyan, JR
    Holst, CL
    Johnson, AJ
    Schwenk, CM
    JOURNAL OF ORGANIC CHEMISTRY, 2002, 67 (07): : 2263 - 2265
  • [8] Total Synthesis of Aphadilactones A-D
    Yin, Jian-Peng
    Gu, Min
    Li, Ying
    Nan, Fa-Jun
    JOURNAL OF ORGANIC CHEMISTRY, 2014, 79 (13): : 6294 - 6301
  • [9] Total synthesis of Carpatamides A-D
    Madala, Nagaraju
    Ghanta, Venkata Rao
    Vinnakota, Srilalitha
    Mendu, Narender
    Ingle, Arun B.
    Ethiraj, Krishna
    Sharma, Vishal
    TETRAHEDRON LETTERS, 2018, 59 (27) : 2708 - 2710
  • [10] Total synthesis of tricyclic marine alkaloids
    Kibayashi, Chihiro
    Aoyagi, Sakae
    Abe, Hideki
    JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 2007, 65 (08) : 805 - 819