Obsessive-compulsive disorder is an uncommon psychopathological condition, characterized by a set of disturbing symptoms that usually disrupts the ongoing behaviour. A growing body of evidence from genetic, brain imaging techniques and psychopharmacological studies links this syndrome to frontal lobe and basal ganglia dysfunction and to the serotonin system. In this article we review the most recent studies exploring the biological, neuropsychological and clinical aspects of obsessive-compulsive disorder.
机构:
Medical Research Council Unit on Anxiety Disorders, University of Stellenbosch, Cape TownMedical Research Council Unit on Anxiety Disorders, University of Stellenbosch, Cape Town
Stein D.J.
Liu Y.
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Medical Research Council Unit on Anxiety Disorders, University of Stellenbosch, Cape TownMedical Research Council Unit on Anxiety Disorders, University of Stellenbosch, Cape Town
Liu Y.
Shapira N.A.
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Medical Research Council Unit on Anxiety Disorders, University of Stellenbosch, Cape TownMedical Research Council Unit on Anxiety Disorders, University of Stellenbosch, Cape Town
Shapira N.A.
Goodman W.K.
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Medical Research Council Unit on Anxiety Disorders, University of Stellenbosch, Cape TownMedical Research Council Unit on Anxiety Disorders, University of Stellenbosch, Cape Town
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North West Univ, Sch Pharm, Div Pharmacol, ZA-2520 Potchefstroom, South AfricaNorth West Univ, Sch Pharm, Div Pharmacol, ZA-2520 Potchefstroom, South Africa
Korff, Schaun
Harvey, Brian H.
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North West Univ, Sch Pharm, Div Pharmacol, ZA-2520 Potchefstroom, South AfricaNorth West Univ, Sch Pharm, Div Pharmacol, ZA-2520 Potchefstroom, South Africa