Ivosidenib (AG-120) in Patients with IDH1-Mutant Relapsed/Refractory Myelodysplastic Syndrome: Updated Enrollment of a Phase 1 Dose Escalation and Expansion Study

被引：14

作者：

Foran, James M. ^{[1
]}

DiNardo, Courtney D. ^{[2
]}

Watts, Justin M. ^{[3
]}

Stein, Eytan M. ^{[4
]}

De Botton, Stephane ^{[5
]}

Fathi, Amir T. ^{[6
]}

Prince, Gabrielle T. ^{[7
]}

Stein, Anthony ^{[8
]}

Stone, Richard M. ^{[9
]}

Patel, Prapti A. ^{[10
]}

Tallman, Martin S. ^{[4
]}

Choe, Sung ^{[11
]}

Wang, Hongfang ^{[11
]}

Zhang, Vickie ^{[11
]}

Fan, Bin ^{[11
]}

Yen, Katharine E. ^{[11
]}

Oluyadi, Abdulafeez ^{[11
]}

Winkler, Thomas ^{[11
]}

Hickman, Denice ^{[11
]}

Agresta, Samuel V. ^{[11
]}

Liu, Hua ^{[11
]}

Wu, Bin ^{[11
]}

Attar, Eyal C. ^{[11
]}

Kantarjian, Hagop M. ^{[2
]}

机构：

[1] Mayo Clin Florida, Jacksonville, FL USA

[2] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA

[3] Univ Miami, Sylvester Comprehens Canc Ctr, Miami, FL USA

[4] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA

[5] Inst Gustave Roussy, Villejuif, France

[6] Massachusetts Gen Hosp, Canc Ctr, Boston, MA 02114 USA

[7] Johns Hopkins Univ Hosp, Baltimore, MD 21287 USA

[8] City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USA

[9] Dana Farber Canc Inst, Boston, MA 02115 USA

[10] Univ Texas Southwestern Med Ctr Dallas, Dallas, TX 75390 USA

[11] Agios Pharmaceut Inc, Cambridge, MA USA

来源：

BLOOD | 2019年 / 134卷

关键词：

D O I：

10.1182/blood-2019-123946

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

4254

引用

页数：4

共 50 条

[1] Ivosidenib (IVO; AG-120) in IDH1-Mutant Relapsed or Refractory Myelodysplastic Syndrome: Updated Results from a Phase 1 Study
DiNardo, Courtney D.
Foran, James M.
Watts, Justin M.
Stein, Eytan M.
De Botton, Stephane
Fathi, Amir T.
Prince, Gabrielle T.
Stein, Anthony S.
Stone, Richard M.
Patel, Prapti A.
Tallman, Martin S.
Choe, Sung
Wang, Hongfang
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CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2019, 19 : S340 - S340
[2] Ivosidenib (IVO) in Patients with IDH1-Mutant Relapsed/Refractory Myelodysplastic Syndrome (R/R MDS): Updated Enrollment of a Phase 1 Dose Escalation and Expansion Study
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[3] Ivosidenib (AG-120) Induced Durable Remissions and Transfusion Independence in Patients with IDH1-Mutant Relapsed or Refractory Myelodysplastic Syndrome: Results from a Phase 1 Dose Escalation and Expansion Study
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[4] Ivosidenib in patients with IDH1-mutant relapsed/refractory myelodysplastic syndrome (R/R MDS): Updated enrollment and results of a phase 1 dose-escalation and expansion substudy.
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[5] Ivosidenib (AG-120) Induced Durable Remissions and Transfusion Independence in Patients with IDH1-Mutant Untreated AML: Results from a Phase 1 Dose Escalation and Expansion Study
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[6] Ivosidenib (IVO) in Patients with IDH1-Mutant Relapsed/Refractory Myelodysplastic Syndrome (R/R MDS): Updated Enrollment for the MDS Sub-Study
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[7] Ivosidenib (AG-120) in Mutant IDH1 AML and Advanced Hematologic Malignancies: Results of a Phase 1 Dose Escalation and Expansion Study
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[8] Ivosidenib (AG-120) in Mutant IDH1 Relapsed/Refractory Acute Myeloid Leukemia: Results of a Phase 1 Study
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Pollyea, Daniel A.
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[9] Population Pharmacokinetics of Ivosidenib (AG-120) in Patients with IDH1-Mutant Advanced Hematologic Malignancies
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