Intensive nutritional care for patients treated with radiotherapy in head and neck cancer: a randomized study and meta-analysis

被引：17

作者：

Roussel, Lise-Marie ^{[1
]}

Micault, Emmanuel ^{[1
]}

Peyronnet, Damien ^{[2
]}

Blanchard, David ^{[3
]}

Guarnieri, Severine ^{[4
]}

Choussy, Olivier ^{[5
]}

Gery, Bernard ^{[6
]}

Bequignon, Arnaud ^{[7
]}

Joubert, Corinne ^{[8
]}

Parienti, Jean-Jacques ^{[9
]}

Babin, Emmanuel ^{[10
]}

机构：

[1] CHU Caen, Dept Otolaryngol Head & Neck Surg, Ave Cote Nacre, F-14000 Caen, France

[2] CHU Caen, Dept Pharm, Ave Cote Nacre, Caen, France

[3] Ctr Francois Baclesse, Dept Head & Neck Surg, Ave Gen Harris, Caen, France

[4] Ctr Tubiana, Dept Radiotherapy, Rue Capitaine Guynemer, Caen, France

[5] CHU Rouen, Dept Otolaryngol Head & Neck Surg, Rue Germont, Rouen, France

[6] Ctr Francois Baclesse, Dept Radiotherapy, Ave Gen Harris, Caen, France

[7] Ctr Tubiana, Dept Otolaryngol Head & Neck Surg, Rue Capitaine Guynemer, Caen, France

[8] CHU Caen, Dept Nutr, Ave Cote Nacre, Caen, France

[9] CHU Caen, Dept Biotat & Clin Res, Ave Cote Nacre, Caen, France

[10] INSERM, U Canc & Prevent 1086, Ave Cote Nacre, Caen, France

来源：

EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY | 2017年 / 274卷 / 02期

关键词：

Malnutrition; Quality of life; Head and neck neoplasms; Radiotherapy; QUALITY-OF-LIFE; OUTPATIENTS RECEIVING RADIOTHERAPY; FOOD-INTAKE; ENTERAL NUTRITION; ONCOLOGY; CHEMORADIOTHERAPY; THERAPY; IMPACT; INTERVENTIONS; MALNUTRITION;

D O I：

10.1007/s00405-016-4278-9

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Nutritional care improves quality of life (QOL) in head and neck cancer patients treated with radiotherapy. The aim of our study was to determine whether intensive nutritional care (INC) would further improve QOL. In addition to a control group based on European and American guidelines, patients included in the INC group received six meetings with a dietitian. QOL was measured after radiotherapy using the EORTC QLQ-C30. We performed a meta-analysis to determine the best nutritional care. In the 87 patients, the QOL scores, weight, energy, and protein intakes were similar between the INC group (n = 43) and the control group (n = 44). The meta-analysis revealed no heterogeneity and significant differences in QOL (three studies) (p = 0.46) or weight changes after radiotherapy (four studies) (p = 0.06). The nutritional care specified in the European and American guidelines is composed of well-defined recommendations, and appears sufficient to maintain QOL without further intervention.

引用

页码：977 / 987

页数：11

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