An Articulate Oxidative Transition-Metal-Free Homocoupling of Imidazo Heterocycles through C(sp2)-C(sp2) Bond Formation

被引：16
|
作者：
Shakoor, S. M. Abdul [1 ]
Mandal, Sanjay K. [2 ]
Sakhuja, Rajeev [1 ]
机构：
[1] Birla Inst Technol & Sci, Dept Chem, Pilani 333031, Rajasthan, India
[2] Indian Inst Sci Educ & Res Mohali, Dept Chem Sci, Sect 81,Manuali PO, Sas Nagar 140306, Punjab, India
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 2017卷 / 18期
关键词：
C-H activation; Hypervalent compounds; Homocoupling; Nitrogen heterocycles; Iodine reagents; C-H ACTIVATION; COUPLING REACTIONS; AMBIENT-TEMPERATURE; METHYLENE SOURCE; IODINE REAGENTS; IMIDAZOHETEROCYCLES; FUNCTIONALIZATION; DERIVATIVES; AMINATION; ARENES;
D O I：
10.1002/ejoc.201700238
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Direct oxidative homocoupling of 2-arylimidazo heterocycles was achieved by using a phenyliodine diacetate-mediated BF3<bold>OEt</bold>2-accelerated protocol at room temperature. A series of biimidazo heterocycles were synthesized under ambient conditions without prior activation of the C(sp(2))-H bond. The desired biimidazo heterocycles were also obtained by using catalytic amounts of iodobenzene and m-CPBA/AcOH in an organocatalytic fashion.
引用
收藏
页码：2596 / 2602
页数：7
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