Synergistic activity of ABT-263 and ONC201 against solid tumor cell lines is associated with suppression of BAG3, Mcl-1, pAkt, and upregulation of Noxa along with Bax cleavage during apoptosis

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作者
Di Cristofano, Francesca R. [1 ]
Fong, Mara [1 ]
Zhou, Lanlan [1 ]
El-Deiry, Wafik S. [1 ]
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[1] Brown Univ, Ctr Canc, Warren Alpert Med Sch, Providence, RI USA
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R73 [肿瘤学];
学科分类号
100214 ;
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3709
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页数:2
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  • [1] Synergistic activity of ABT-263 and ONC201/TIC10 against solid tumor cell lines is associated with suppression of anti-apoptotic Mcl-1, BAG3, pAkt, and upregulation of pro-apoptotic Noxa and Bax cleavage during apoptosis
    Di Cristofano, Francesca R.
    Fong, Mara W.
    Huntington, Kelsey E.
    Carneiro, Benedito A.
    Zhou, Lanlan
    El-Deiry, Wafik S.
    AMERICAN JOURNAL OF CANCER RESEARCH, 2023, 13 (01): : 307 - 325