A structured summary of a study protocol for a multi-center, randomized controlled trial (RCT) of COVID-19 prevention with Kampo medicines (Integrative Management in Japan for Epidemic Disease by prophylactic study: IMJEDI P1 study)

被引：9

作者：

Namiki, Takao ^{[1
]}

Takayama, Shin ^{[2
,3
,4
]}

Arita, Ryutaro ^{[2
,3
]}

Ishii, Tadashi ^{[2
,3
,4
]}

Kainuma, Mosaburo ^{[5
]}

Makino, Toshiaki ^{[6
]}

Mimura, Masaru ^{[7
]}

Yoshino, Tetsuhiro ^{[8
]}

Nogami, Tatsuya ^{[9
]}

Arai, Makoto ^{[9
]}

Sato, Juichi ^{[10
]}

Tanaka, Koichiro ^{[11
]}

Nakae, Hajime ^{[12
]}

Igari, Hidetoshi ^{[13
]}

Ozawa, Yoshihito ^{[14
]}

Shiko, Yuki ^{[14
]}

Kawasaki, Yohei ^{[15
]}

Nezu, Masahiko ^{[1
]}

Ito, Takashi ^{[16
]}

机构：

[1] Chiba Univ, Grad Sch Med, Dept Japanese Oriental Kampo Med, Chuo Ku, 1-8-1 Inohana, Chiba 2608670, Japan

[2] Tohoku Univ Hosp, Dept Kampo Med, Aoba Ku, 1-1 Seiryo Machi, Sendai, Miyagi 9808574, Japan

[3] Tohoku Univ Hosp, Dept Educ & Support Reg Med, Aoba Ku, 1-1 Seiryo Machi, Sendai, Miyagi 9808574, Japan

[4] Tohoku Univ, Grad Sch Med, Dept Kampo & Integrat Med, Aoba Ku, 1-2 Seiryo Machi, Sendai, Miyagi 9808575, Japan

[5] Kyushu Univ, Grad Sch Med Sci, Community Med Educ Unit, Higashi Ku, 3-1-1 Maidashi, Fukuoka 8128582, Japan

[6] Nagoya City Univ, Grad Sch Pharmaceut Sci, Dept Pharmacognosy, Mizuho Ku, 3-1 Tanabe Dori, Nagoya, Aichi 4678603, Japan

[7] Keio Univ, Sch Med, Dept Neuropsychiat, Shinjuku Ku, 35 Shinanomachi, Tokyo 1608582, Japan

[8] Keio Univ, Sch Med, Ctr Kampo Med, Shinjuku Ku, 35 Shinanomachi, Tokyo 1608582, Japan

[9] Tokai Univ, Sch Med, Dept Kampo Med, 143 Shimokasuya, Isehara, Kanagawa 2591193, Japan

[10] Nagoya Univ, Grad Sch Med, Dept Gen Med Family & Community Med, Showa Ku, 65 Tsurumai Cho, Nagoya, Aichi 4668550, Japan

[11] Toho Univ, Fac Med, Dept Tradit Med, Ota Ku, 5-21-16 Omorinishi, Tokyo 1438540, Japan

[12] Akita Univ, Grad Sch Med, Dept Emergency & Crit Care Med, 44-2 Hasunuma Hiroomote, Akita 0108543, Japan

[13] Chiba Univ, Chiba Univ Hosp, Sch Med, Dept Infect Dis,Chuo Ku, 1-8-1 Inohana, Chiba 2608677, Japan

[14] Chiba Univ Hosp, Clin Res Ctr, Biostat Sect, Chuo Ku, 1-8-1 Inohana, Chiba 2608677, Japan

[15] Japanese Red Cross Coll Nursing, Fac Nursing, Tokyo 1500012, Japan

[16] Akashi Clin Kanda, Chiyoda Ku, 3-8 Kandaogawamachi, Tokyo 1010052, Japan

来源：

TRIALS | 2021年 / 22卷 / 01期

关键词：

COVID-19; randomized controlled trial; protocol; Kampo medicines; prophylactic study;

D O I：

10.1186/s13063-020-04939-2

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页数：3

共 50 条

[1] A structured summary of a study protocol for a multi-center, randomized controlled trial (RCT) of COVID-19 prevention with Kampo medicines (Integrative Management in Japan for Epidemic Disease by prophylactic study: IMJEDI P1 study)
Takao Namiki
Shin Takayama
Ryutaro Arita
Tadashi Ishii
Mosaburo Kainuma
Toshiaki Makino
Masaru Mimura
Tetsuhiro Yoshino
Tatsuya Nogami
Makoto Arai
Juichi Sato
Koichiro Tanaka
Hajime Nakae
Hidetoshi Igari
Yoshihito Ozawa
Yuki Shiko
Yohei Kawasaki
Masahiko Nezu
Takashi Ito
[J]. Trials, 22
[2] A multi-center, randomized controlled trial by the Integrative Management in Japan for Epidemic Disease (IMJEDI study-RCT) on the use of Kampo medicine, kakkonto with shosaikotokakikyosekko, in mild-to-moderate COVID-19 patients for symptomatic relief and prevention of severe stage: a structured summary of a study protocol for a randomized controlled trial
Takayama, Shin
Namiki, Takao
Ito, Takashi
Arita, Ryutaro
Nakae, Hajime
Kobayashi, Seiichi
Yoshino, Tetsuhiro
Ishigami, Tomoaki
Tanaka, Koichiro
Kainuma, Mosaburo
Nochioka, Kotaro
Takagi, Airi
Mimura, Masaru
Yamaguchi, Takuhiro
Ishii, Tadashi
[J]. TRIALS, 2020, 21 (01)
[3] A multi-center, randomized controlled trial by the Integrative Management in Japan for Epidemic Disease (IMJEDI study-RCT) on the use of Kampo medicine, kakkonto with shosaikotokakikyosekko, in mild-to-moderate COVID-19 patients for symptomatic relief and prevention of severe stage: a structured summary of a study protocol for a randomized controlled trial
Shin Takayama
Takao Namiki
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Hajime Nakae
Seiichi Kobayashi
Tetsuhiro Yoshino
Tomoaki Ishigami
Koichiro Tanaka
Mosaburo Kainuma
Kotaro Nochioka
Airi Takagi
Masaru Mimura
Takuhiro Yamaguchi
Tadashi Ishii
[J]. Trials, 21
[4] Conventional and Kampo medicine in the treatment of mild to moderate COVID-19: A multicenter, retrospective observational study protocol by the Integrative Management in Japan for Epidemic Disease (IMJEDI study-Observation)
Takayama, Shin
Kashima, Masayuki
Namiki, Takao
Ito, Takashi
Ono, Rie
Arita, Ryutaro
Saito, Natsumi
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Irie, Yasuhito
Kobayashi, Seiichi
Yoshino, Tetsuhiro
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Minakawa, Satoko
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Koizumi, Sayaka
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Ishii, Tadashi
[J]. TRADITIONAL & KAMPO MEDICINE, 2021, 8 (01) : 106 - 110
[5] Conventional and Kampo Medicine Treatment for Mild-to-moderate COVID-19: A Multicenter, Retrospective, Observational Study by the Integrative Management in Japan for Epidemic Disease (IMJEDI Study-observation)
Takayama, Shin
Yoshino, Tetsuhiro
Koizumi, Sayaka
Irie, Yasuhito
Suzuki, Tomoko
Fujii, Susumu
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Kobayashi, Seiichi
Nogami, Tatsuya
Yokota, Kenichi
Yamazaki, Mayuko
Minakawa, Satoko
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Suda, Norio
Nakada, Yoshinobu
Ishige, Tatsuya
Maehara, Hirofumi
Tanaka, Yutaka
Nagase, Mahiko
Kashio, Akihiko
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Shimooki, Osamu
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Arita, Ryutaro
Ono, Rie
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Kikuchi, Akiko
Ohsawa, Minoru
Nakae, Hajime
Mitsuma, Tadamichi
Mimura, Masaru
Ishii, Tadashi
Nochioka, Kotaro
Chiu, Shih-Wei
Yamaguchi, Takuhiro
Namiki, Takao
Hisanaga, Akito
Mitani, Kazuo
Ito, Takashi
[J]. INTERNAL MEDICINE, 2023, 62 (02) : 187 - 199
[6] Homeopathy for Covid-19 in Primary Care: A structured summary of a study protocol for a randomized controlled trial
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Katia Regina Spiller
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[J]. Trials, 22
[7] Homeopathy for Covid-19 in Primary Care: A structured summary of a study protocol for a randomized controlled trial
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Hotta, Livia Mitchiguian
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Martins Diniz, Jose Nelson
Antonio Mestre, Crislaine Aparecida
Spiller, Katia Regina
Soares, Lidiamara
Santos, Helen de Freitas
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[J]. TRIALS, 2021, 22 (01)
[8] Ivermectin to prevent hospitalizations in patients with COVID-19 (IVERCOR-COVID19): a structured summary of a study protocol for a randomized controlled trial
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Rodrigo Zoni
Maria Bangher
Silvina Villamandos
Angelina Bobadilla
Fabian Plano
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Fernando Achinelli
Hector A. Guglielmone
Jorge Ojeda
Fernanda Medina
Diego Farizano Salazar
Gerardo Andino
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Elba Meza
Silvana Dellamea
Antonia Aquino
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Carolina N. Martemucci
María Mercedes Vernengo
Silvina María Martinez
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María Gabriela Aguirre
[J]. Trials, 21
[9] Ivermectin to prevent hospitalizations in patients with COVID-19 (IVERCOR-COVID19): a structured summary of a study protocol for a randomized controlled trial
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Zoni, Rodrigo
Bangher, Maria
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Chaparro Campias, Evangelina
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Ojeda, Jorge
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Farizano Salazar, Diego
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Kawerin, Pablo
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Dellamea, Silvana
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Flores, Victor
Martemucci, Carolina N.
Vernengo, Maria Mercedes
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[J]. TRIALS, 2020, 21 (01)
[10] The efficacy and safety of Ivermectin in patients with mild and moderate COVID-19: A structured summary of a study protocol for a randomized controlled trial
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[J]. Trials, 22

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