Ustekinumab for Refractory Colitis Associated with Immune Checkpoint Inhibitors

被引:60
|
作者
Thomas, Anusha S. [1 ]
Ma, Weijie [2 ]
Wang, Yinghong [1 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
[2] Zhongnan Hosp, Wuhan, Peoples R China
来源
NEW ENGLAND JOURNAL OF MEDICINE | 2021年 / 384卷 / 06期
关键词
D O I
10.1056/NEJMc2031717
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Two patients in whom severe refractory autoimmune colitis developed after cancer treatment with immune checkpoint inhibitors had a response to a course of subcutaneously administered ustekinumab, an antibody that blocks interleukin-12/23 signaling.
引用
收藏
页码:581 / 583
页数:3
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