Synthesis of new cyclopropylisonitriles and their applications in Ugi four-component reactions

被引：9
|
作者：
Osipova, Anna
Yufit, Dmitrii S.
de Meijere, Armin
机构：
[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany
[2] Univ Durham, Dept Chem, Durham DH1 3LE, England
来源：
SYNTHESIS-STUTTGART | 2007年 / 01期
关键词：
ring constructions; titanium chemistry; multicomponent reactions; dipeptides; isonitriles;
D O I：
10.1055/s-2006-958927
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Several new cyclopropylisonitriles were synthesized from the corresponding cyclopropylamines (41-69% yield) and utilized in Ugi four-component reactions to famish 12 new dipeptides in 38-86% yield. The structures of four of these dipeptides were determined by X-ray crystallography.
引用
收藏
页码：131 / 139
页数：9
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