A New Golden Age of Natural Products Drug Discovery

被引：497

作者：

Shen, Ben ^{[1
,2
,3
,4
]}

机构：

[1] Scripps Res Inst, Dept Chem, Jupiter, FL 33458 USA

[2] Scripps Res Inst, Dept Mol Therapeut, Jupiter, FL 33458 USA

[3] Scripps Res Inst, Nat Prod Lib Initiat, Jupiter, FL 33458 USA

[4] Cent S Univ, Xiangya Int Acad Translat Med, Changsha 410013, Hunan, Peoples R China

来源：

CELL | 2015年 / 163卷 / 06期

关键词：

ARTEMISININ; IVERMECTIN; QINGHAOSU;

D O I：

10.1016/j.cell.2015.11.031

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The 2015 Nobel Prize in Physiology or Medicine has been awarded to William C. Campbell, Satoshi Omura, and Youyou Tu for the discovery of avermectins and artemisinin, respectively, therapies that revolutionized the treatment of devastating parasite diseases. With the recent technological advances, a New Golden Age of natural products drug discovery is dawning.

引用

页码：1297 / 1300

页数：4

共 50 条

[1] New aspects of natural products in drug discovery
Lam, Kin S.
[J]. TRENDS IN MICROBIOLOGY, 2007, 15 (06) : 279 - 289
[2] New natural products as new leads for antibacterial drug discovery
Brown, Dean G.
Lister, Troy
May-Dracka, Tricia L.
[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 24 (02) : 413 - 418
[3] Natural products drug discovery - New technologies and approaches
Stead, P
[J]. DRUG DISCOVERY TODAY, 1997, 2 (07) : 256 - 259
[4] Natural products in drug discovery – Creating a new vision
Geoffrey A. Cordell
[J]. Phytochemistry Reviews, 2002, 1 (3) : 261 - 273
[5] New drug discovery from microbial natural products
Sunazuka, Toshiaki
[J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 231
[6] Natural products in drug discovery
Roggo, Silvio
[J]. CHIMIA, 2007, 61 (06) : 312 - 312
[7] Natural products in drug discovery
Müller, H
Brackhagen, O
Brunne, R
Henkel, L
Reichel, F
[J]. ROLE OF NATURAL PRODUCTS IN DRUG DISCOVERY, 2000, 32 : 205 - 216
[8] Natural products and drug discovery
Newman, David J.
[J]. NATIONAL SCIENCE REVIEW, 2022, 9 (11)
[9] Natural products and drug discovery
David J.Newman
[J]. National Science Review, 2022, 9 (11) : 37 - 57
[10] Natural products for drug discovery
Marrero, Faz E.
[J]. TOXICOLOGY LETTERS, 2016, 259 : S15 - S15

← 1 2 3 4 5 →