C-13-NMR and mass spectral data of steroids with a 17,17-dialkyl-18-nor-13(14)-ene substructure

被引：0
|
作者：
DeBrabandere, VI
Thienpont, LM
Stockl, D
DeLeenheer, AP
机构：
[1] STATE UNIV GHENT,LAB MED BIOCHEM KLIN ANALYSE,B-9000 GHENT,BELGIUM
[2] STATE UNIV GHENT,ANALYT CHEM LAB,B-9000 GHENT,BELGIUM
来源：
JOURNAL OF LIPID RESEARCH | 1997年 / 38卷 / 04期
关键词：
Wagner-Meerwein rearrangement; mass spectrometry; heptafluorobutyrilation;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
We present carbon-13 nuclear magnetic resonance (C-13-NMR) and mass spectral data for several androstanes and estranes having a 17,17-dialkyl-18-nor-13 (14)-ene substructure. These compounds are formed by a Wagner-Meerwein rearrangement of steroids bearing a tertiary 17-hydroxy group during the derivatization reaction with heptafluorobutyric anhydride. The C-13-NMR assignments are compared with those of natural products having a similar substructure. The mass spectra show characteristic fragment ions for which a fragmentation mechanism is proposed.
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收藏
页码：780 / 789
页数：10
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