Synthesis and heterocyclization of triterpenic 1,3-diketones

被引：4

作者：

Nazarov, Mikhail A. ^{[1
]}

Tolmacheva, Irina A. ^{[1
]}

Grishko, Victoria V. ^{[1
]}

机构：

[1] Perm Fed Sci Ctr, Acad Korolev St 3, Perm 614013, Russia

来源：

ARKIVOC | 2020年

关键词：

Triterpenoids; aldehydes; aldol condensation; 1,3-diketones; pyrazoles; isoxazoles; BETULINIC ACID-DERIVATIVES; BIOLOGICAL EVALUATION; IN-VITRO; INHIBITORS; ANTITUMOR;

D O I：

10.24820/ark.5550190.p011.344

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Procedures for the synthesis of some new lupane and 18 alpha H-oleanane pyrazole and isoxazole derivatives from betulin are reported. The synthetic scheme for the preparation of 1,2-azoles involves aldol condensation of triterpenic aldehydes with acetone as a key stage. [GRAPHICS]

引用

页码：70 / 80

页数：11

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