SYNTHESIS, CHARACTERIZATION, AND BIOLOGICAL ACTIVITY OF A NEW CLASS OF DIALKYLPHOSPHORYLHYDRAZONE DERIVATIVES OF ISATIN

被引:5
|
作者
Zampirolli, Leticia Silotti [1 ]
de Lemos, Marcela Jacques [1 ]
Goncalves, Vinicius Tomaz [1 ,2 ]
Alves de Souza, Marco Andre [1 ]
de Souza, Sonia Regina [1 ]
Rumjanek, Victor Marcos [1 ]
DaCosta, Joao Batista Neves [1 ]
机构
[1] Univ Fed Rural Rio de Janeiro, Inst Ciencias Exatas, Dept Quim, BR-23890000 Seropedica, RJ, Brazil
[2] Ctr Fed Educ Tecnol Celso Suckow da Fonseca, Itaguai, RJ, Brazil
来源
QUIMICA NOVA | 2014年 / 37卷 / 06期
关键词
dialkylphosphorylhydrazones; isatins; biological activity; NATURAL-PRODUCTS; INHIBITION; PROTEINS; GROWTH;
D O I
10.5935/0100-4042.20140162
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Sixteen dialkylphosphorylhydrazones were synthesized by condensation of phosphorylhydrazines with substituted isatins. Products were characterized by FTIR, H-1-NMR, C-13-NMR, and P-31-NMR. Fungicidal activities of these compounds against Rhizoctonia solani and Fusarium oxysporum were also evaluated. Some compounds inhibited the growth of Rhizoctonia solani and Fusarium oxysporum by 43% and 51%, respectively. These compounds exhibited no effects on germination of lettuce seeds (Lactuca sativa L).
引用
收藏
页码:989 / U120
页数:46
相关论文
共 50 条
  • [1] Synthesis, Characterization, and Antibacterial Activity of New Isatin Derivatives
    Sumitra Nain
    Garima Mathur
    Tulika Anthwal
    Swapnil Sharma
    Sarvesh Paliwal
    Pharmaceutical Chemistry Journal, 2023, 57 : 196 - 203
  • [2] Synthesis, Characterization, and Antibacterial Activity of New Isatin Derivatives
    Nain, Sumitra
    Mathur, Garima
    Anthwal, Tulika
    Sharma, Swapnil
    Paliwal, Sarvesh
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2023, 57 (02) : 196 - 203
  • [3] A survey on the characterization and biological activity of isatin derivatives
    Drmanic, Sasa Z.
    Petrovic, Predrag
    Brkic, Dominik R.
    Marinkovic, Aleksandar D.
    Nikolic, Jasmina B.
    JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, 2020, 85 (08) : 979 - 1000
  • [4] Synthesis and biological evaluation of new bis isatin derivatives for CNS activity
    Manchala, Lalitha
    Tatipelly, Madhukar Reddy
    Andole, Sowmya
    Manda, Sarangapani
    Devarakonda, Krishna Prasad
    Arukula, Ravi
    Gangarapu, Kiran
    MATERIALS TODAY-PROCEEDINGS, 2022, 64 : 903 - 908
  • [5] Synthesis and biological evaluation of new bis isatin derivatives for CNS activity
    Manchala, Lalitha
    Tatipelly, Madhukar Reddy
    Andole, Sowmya
    Manda, Sarangapani
    Devarakonda, Krishna Prasad
    Arukula, Ravi
    Gangarapu, Kiran
    MATERIALS TODAY-PROCEEDINGS, 2022, 64 : 903 - 908
  • [6] Synthesis, Structure-Activity Relationships and Biological Activity of New Isatin Derivatives as Tyrosinase Inhibitors
    Gencer, Nahit
    Sonmez, Fatih
    Demir, Dudu
    Arslan, Oktay
    Kucukislamoglu, Mustafa
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2014, 14 (12) : 1450 - 1462
  • [7] Synthesis, Characterization and Antibacterial Activity of Carbamate Derivatives of Isatin
    Jabbar, Sarrah Sattar
    ORIENTAL JOURNAL OF CHEMISTRY, 2018, 34 (04) : 2026 - 2030
  • [8] Synthesis, characterization and biological activities of some novel isatin derivatives
    Amani, A. M.
    BULGARIAN CHEMICAL COMMUNICATIONS, 2014, 46 (04): : 795 - 800
  • [9] Synthesis, biological activity and docking study of some new isatin Schiff base derivatives
    Azizian, Javad
    Mohammadi, Mohammad K.
    Firuzi, Omidreza
    Razzaghi-asl, Nima
    Miri, Ramin
    MEDICINAL CHEMISTRY RESEARCH, 2012, 21 (11) : 3730 - 3740
  • [10] Synthesis, biological activity and docking study of some new isatin Schiff base derivatives
    Javad Azizian
    Mohammad K. Mohammadi
    Omidreza Firuzi
    Nima Razzaghi-asl
    Ramin Miri
    Medicinal Chemistry Research, 2012, 21 : 3730 - 3740