HIGHLY CONTROLLABLE THREE-DIMENSIONAL SHEATH FLOW DEVICE FOR FABRICATION OF ARTIFICIAL CAPILLARY VESSELS

被引:0
|
作者
Ito, J. [1 ]
Sekine, R. [1 ]
Yoon, D. H. [1 ]
Nakamura, Y. [2 ]
Oku, H. [2 ]
Nansai, H. [2 ]
Chikasawa, T. [2 ]
Goto, T. [2 ]
Sekiguchi, T. [3 ]
Takeda, N. [2 ]
Shoji, S. [1 ]
机构
[1] Waseda Univ, Nanosci & Nanoengn, Tokyo, Japan
[2] Waseda Univ, Life Sci & Med Biosci, Tokyo, Japan
[3] Waseda Univ, Inst Nanosci & Nanotechnol, Tokyo, Japan
关键词
STREAM;
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中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
This paper reports a highly controllable three-dimensional (3D) sheath flow device for fabrication of artificial capillary vessels. Three step sheath injection type 3D flow device which realizes wide core and sheath structure variations by simply flow rate control was applied to fabricate double-layer coaxial Core-Sheath microfibers applicable for long micro capillary vessels by aligning and cultivating vascular endothelial cells. As a result, about a 3-centimeter-long microfiber which has the vascular endothelial cells fused mutually in the center was successfully formed after three days culture.
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页码:480 / 483
页数:4
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