The role of CD4 T cell help for CD8 CTL activation

被引：82
|
作者：
Zhang, Sheng [1 ,4 ]
Zhang, Hongjun [2 ]
Zhao, Jiandong [3 ]
机构：
[1] Shanghai Jiao Tong Univ, Peoples Hosp 1, Shanghai 201620, Peoples R China
[2] Qingdao Univ, Med Sch Hosp, Qingdao 266071, Peoples R China
[3] Fudan Univ, Canc Hosp, Dept Radiat Oncol, Shanghai 200433, Peoples R China
[4] Shanghai Key Lab Pancreat Dis, Shanghai, Peoples R China
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 2009年 / 384卷 / 04期
关键词：
CD4 T cells; CD8 T cells; Signal pathway; FACTOR FAMILY-MEMBER; DENDRITIC CELLS; IN-VIVO; SECONDARY EXPANSION; CUTTING EDGE; MEMORY; GENERATION; LYMPHOCYTES; TRANCE; IL-12;
D O I：
10.1016/j.bbrc.2009.04.134
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
CD4 T cells play an important role in the initiation and persistence of CD8 T cells responses. In this review, we report on and evaluate the mechanisms by which CD4 T cells contribute to activation of CD8 T cells and the signal pathways of the down-streaming events after CD4 T cell help. (C) 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码：405 / 408
页数：4
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