Aryl H-phosphonates .5. A simple method for the synthesis of aminoalkyl H-phosphonate monoesters via transesterification of diphenyl H-phosphonate with amino alcohols

被引：0
|
作者：
Sobkowski, M [1 ]
Stawinski, J [1 ]
Kraszewski, A [1 ]
机构：
[1] UNIV STOCKHOLM,ARRHENIUS LAB,DEPT ORGAN CHEM,S-10691 STOCKHOLM,SWEDEN
来源：
COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS | 1996年 / 61卷
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中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new method for the synthesis of N-dimethoxytritylated aminoalkyl H-phosphonate monoesters is described. It consists of transesterification of diphenyl H-phosphonate with an amino alcohol, hydrolysis of the produced di(aminoalkyl) H-phosphonate diester to the corresponding monoester, followed by its tritylation, and silica gel purification of the final product.
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页码：S238 / S241
页数：4
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