DNA recognition by XR5944, a novel bis-intercalator and potent anticancer drug

被引：0
|
作者：
Lin, Clement [1 ]
Mathad, Raveendra I. [1 ]
Sidell, Neil [2 ]
Yang, Danzhou [1 ]
机构：
[1] Univ Arizona, Tucson, AZ USA
[2] Emory Univ, Atlanta, GA 30322 USA
来源：
CANCER RESEARCH | 2015年 / 75卷
关键词：
D O I：
10.1158/1538-7445.AM2015-2445
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
2445
引用
收藏
页数：1
相关论文
共 50 条
  • [1] DNA Recognition by a Novel Bis-Intercalator, Potent Anticancer Drug XR5944
    Lin, Clement
    Yang, Danzhou
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2015, 15 (14) : 1385 - 1397
  • [2] Novel DNA Bis-Intercalator XR5944 as a Potent Anticancer Drug-Design and Mechanism of Action
    Buric, Adam J.
    Dickerhoff, Jonathan
    Yang, Danzhou
    MOLECULES, 2021, 26 (14):
  • [3] Solution structure of a 2: 1 complex of anticancer drug XR5944 with TFF1 estrogen response element: Insights into DNA recognition by a bis-intercalator
    Lin, Clement
    Mathad, Raveendra
    Sidell, Neil
    Yang, Danzhou
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 249
  • [4] Solution structure of a 2:1 complex of anticancer drug XR5944 with TFF1 estrogen response element: insights into DNA recognition by a bis-intercalator
    Lin, Clement
    Mathad, Raveendra I.
    Zhang, Zhenjiang
    Sidell, Neil
    Yang, Danzhou
    NUCLEIC ACIDS RESEARCH, 2014, 42 (09) : 6012 - 6024
  • [5] XR5944: A potent inhibitor of estrogen receptors
    Punchihewa, Chandanamali
    De Alba, Adrian
    Sidell, Neil
    Yang, Danzhou
    MOLECULAR CANCER THERAPEUTICS, 2007, 6 (01) : 213 - 219
  • [6] Synthesis and Anticancer Properties of a Novel Bis-intercalator
    Shen, Wei
    Deng, Huimin
    Gao, Zhiqiang
    ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2013, 13 (04) : 632 - 638
  • [7] XR5944 is a potent inhibitor of estrogen receptors through a novel mechanism
    Punchihewa, Chandanamali
    Carver, Megan
    De Alba, Adrian
    Sidell, Neil
    Yang, Danzhou
    CANCER RESEARCH, 2008, 68 (09)
  • [8] Antitumor activity of XR5944, a novel and potent topoisomerase poison
    Stewart, AJ
    Mistry, P
    Dangerfield, W
    Bootle, D
    Baker, M
    Kofler, B
    Okiji, S
    Baguley, BC
    Denny, WA
    Charlton, PA
    ANTI-CANCER DRUGS, 2001, 12 (04) : 359 - 367
  • [9] Mode of action of the novel phenazine anticancer agents XR11576 and XR5944
    Lewis, Louisa J.
    Mistry, Prakash
    Charlton, Peter A.
    Thomas, Hilary
    Coley, Helen M.
    ANTI-CANCER DRUGS, 2007, 18 (02) : 139 - 148
  • [10] The in vitro antitumour activity of XR5944, a novel, potent topoisomerase inhibitor
    Lancashire, H
    Bootle, DE
    Baker, MB
    Mistry, P
    Liddle, C
    Dangerfield, W
    Denny, WA
    Charlton, PA
    BRITISH JOURNAL OF CANCER, 2000, 83 : 69 - 69
12345