Expression of nitric oxide synthases in the mouse and human nasal mucosa

被引:11
|
作者
Sakai, M [1 ]
Sawada, T [1 ]
Nishimura, T [1 ]
Nagatsu, I [1 ]
机构
[1] FUJITA HLTH UNIV, SCH MED, DEPT OTOLARYNGOL, TOYOAKE, AICHI 47011, JAPAN
关键词
nitric oxide; superoxide dismutase; immunohistochemistry; airway;
D O I
10.1267/ahc.29.177
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
An immunohistochemical study was performed to detect the localization of neural-type nitric oxide synthase (nNOS), endothelial-type NOS (eNOS) and inducible-type NOS (iNOS) in the mouse and human nasal mucosa. nNOS-immunoreactive nerve fibers were observed in the subepithelial layer and around the seromucous glands of mice. In these fibers, immunodouble staining revealed colocalization of nNOS and superoxide dismutase. In the human nasal cavity, strong eNOS immunoreactivity and weak iNOS immunoreactivity were found in the columnar epithelium.
引用
收藏
页码:177 / 179
页数:3
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