Cutaneous adnexal and salivary gland tumours. Similarities and differences

被引:4
|
作者
Ihrler, S. [1 ,2 ]
Weiler, C. [3 ]
Eckert, F. [1 ]
Mollenhauer, M. [4 ]
机构
[1] Lab Dermatohistol & Oralpathol, D-80335 Munich, Germany
[2] Univ Munich, Inst Pathol, D-80539 Munich, Germany
[3] Karl Olga Krankenhaus, Praxis Pathol, Stuttgart, Germany
[4] Tech Univ Munich, Inst Pathol, D-80290 Munich, Germany
来源
PATHOLOGE | 2014年 / 35卷 / 05期
关键词
Histological analogies; Multistep carcinogenesis; Pleomorphic adenoma; Mixed tumor; Spiradenoma; LYMPHOEPITHELIOMA-LIKE CARCINOMA; EX PLEOMORPHIC ADENOMA; MIXED TUMOR; IMMUNOHISTOCHEMICAL ANALYSIS; MUCINOUS CARCINOMA; SKIN ADNEXAL; NEOPLASMS; LYMPHADENOMA; SPIRADENOCYLINDROMA; SPIRADENOMA;
D O I
10.1007/s00292-014-1929-8
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Despite major discrepancies in basic microscopic anatomy, remarkable similarities are manifest within the wide spectrum of cutaneous adnexal and salivary gland tumors. In this study salivary gland and adnexal tumors were identified and investigated with respect to similarities in histology, terminology and pathogenesis. Histological similarities of certain types of salivary gland tumors relate to eccrine, apocrine and rarely sebaceous (but not trichofollicular) types of adnexal tumors. The most striking similarity was found with salivary gland pleomorphic adenoma and cutaneous mixed tumor. Multistep carcinogenesis starting with intraductal carcinoma, identified in carcinoma ex pleomorphic adenoma is identical to that found in cutaneous carcinoma ex spiradenoma. Further histological and terminological similarities are shown for mucinous and mucoepidermoid carcinoma, for lymphadenoma and lymphoepithelial carcinoma, for sebaceous adenoma and carcinoma, for adenoid-cystic carcinoma, as well as for salivary gland basal cell adenoma versus cutaneous spiradenoma. Manifest diagnostic problems related to histologically similar salivary gland and adnexal tumors are rare and are topographically limited to the parotid and oral areas.
引用
收藏
页码:476 / 486
页数:11
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