Totally implantable enzymatic biofuel cell and brain stimulator operating in bird through wireless communication

被引：43

作者：

Lee, Dahye ^{[1
]}

Jeong, Sung Hee ^{[2
]}

Yun, Seunghyeon ^{[3
]}

Kim, Sunhyo ^{[4
]}

Sung, Jaehoon ^{[3
,5
]}

Seo, Jungmin ^{[3
]}

Son, Suyeon ^{[1
]}

Kim, Ji Tae ^{[1
]}

Susanti, Lina ^{[4
]}

Jeong, Youngseok ^{[4
]}

Park, Sanghyun ^{[4
]}

Seo, Kangmoon ^{[4
]}

Kim, Sung June ^{[3
]}

Chung, Taek Dong ^{[1
,2
,6
]}

机构：

[1] Seoul Natl Univ, Dept Chem, Seoul 08826, South Korea

[2] Seoul Natl Univ, Grad Sch Convergence Sci & Technol, Suwon 16229, Gyeonggi Do, South Korea

[3] Seoul Natl Univ, Dept Elect & Comp Engn, Seoul 08826, South Korea

[4] Seoul Natl Univ, Dept Vet Clin Sci, Seoul 08826, South Korea

[5] Duke Univ, Pratt Sch Engn, Durham, NC 27708 USA

[6] Adv Inst Convergence Technol, Electrochem Lab, Suwon 16229, Gyeonggi Do, South Korea

来源：

BIOSENSORS & BIOELECTRONICS | 2021年 / 171卷

基金：

新加坡国家研究基金会;

关键词：

Neurostimulation; Implantable biofuel cell; Animal brain stimulator; Birds; In vivo; TELEMETRY SYSTEM; GENERATION; INSECT;

D O I：

10.1016/j.bios.2020.112746

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Animals digest food to fuel brain neurometabolism via cellular respiration. This study demonstrates the combination of a biofuel cell (BFC) and an animal brain stimulator (ABS) implanted in a pigeon. Glucose oxidation and oxygen reduction in an enzymatic BFC supplied electrical power to the ABS. Power from the BFC reached 0.12 mW in vitro and 0.08 mW in vivo using only the natural glucose and oxygen in the pigeon's body. A power management integrated circuit is used to harvest energy from the in vivo BFC at a rate of 28.4 mJ over 10 min, which is sufficient for intermittent neurostimulation.

引用

页数：8

共 21 条

[1] Enhancing electrical communication through reconstructed nanowire electrodes for implantable enzymatic biofuel cell (EBFC)
Fapyane, Deby
Lee, Soo-Jin
Lim, Duhyun
Ahn, Jou-Hyeon
Chang, In Seop
[J]. PROCEEDINGS OF THE EIGHTEENTH INTERNATIONAL SYMPOSIUM ON ARTIFICIAL LIFE AND ROBOTICS (AROB 18TH '13), 2013, : 594 - 596
[2] Electrical Circuit Model and Dynamic Analysis of Implantable Enzymatic Biofuel Cells Operating In Vivo
Wey, Todd A.
Southcott, Mark
Jemison, William D.
MacVittie, Kevin
Katz, Evgeny
[J]. PROCEEDINGS OF THE IEEE, 2014, 102 (11) : 1795 - 1810
[3] A wireless millimetre-scale implantable neural stimulator with ultrasonically powered bidirectional communication
Piech, David K.
Johnson, Benjamin C.
Shen, Konlin
Ghanbari, M. Meraj
Li, Ka Yiu
Neely, Ryan M.
Kay, Joshua E.
Carmena, Jose M.
Maharbiz, Michel M.
Muller, Rikky
[J]. NATURE BIOMEDICAL ENGINEERING, 2020, 4 (02) : 207 - 222
[4] A wireless millimetre-scale implantable neural stimulator with ultrasonically powered bidirectional communication
David K. Piech
Benjamin C. Johnson
Konlin Shen
M. Meraj Ghanbari
Ka Yiu Li
Ryan M. Neely
Joshua E. Kay
Jose M. Carmena
Michel M. Maharbiz
Rikky Muller
[J]. Nature Biomedical Engineering, 2020, 4 : 207 - 222
[5] An enzymatic glucose/O2 biofuel cell operating in human blood
Cadet, Marine
Gounel, Sebastien
Stines-Chaumeil, Claire
Brilland, Xavier
Rouhana, Jad
Louerat, Frederic
Mano, Nicolas
[J]. BIOSENSORS & BIOELECTRONICS, 2016, 83 : 60 - 67
[6] Improving upon enzymatic biofuel cell efficient through metabolic enzymatic pathway complexation
Moehlenbrock, Michael J.
Toby, Timothy
Minteer, Shelley D.
[J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2010, 239
[7] Remote wireless control of an enzymatic biofuel cell implanted in a rabbit for 2 months
El Ichi-Ribault, Sarra
Alcaraz, Jean-Pierre
Boucher, Francois
Boutaud, Bertrand
Dalmolin, Renzo
Boutonnat, Jean
Cinquin, Philippe
Zebda, Abdelkader
Martin, Donald K.
[J]. ELECTROCHIMICA ACTA, 2018, 269 : 360 - 366
[8] DEVELOPMENT OF A TOTALLY IMPLANTABLE WIRELESS NEURAL SIGNAL TRANSMISSION SYSTEM (TIWINETS) FOR BRAIN-MACHINE INTERFACE (BMI)
Lee, Hyun Joo
Rhee, Sang Myung
Nyamdorj, Selenge
Lang, Yiran
Ham, Hyun Geol
Jin, Xue Mei
Komissarova, Julia
Ahn, Jae Mok
Shin, Hyung-Cheul
[J]. JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009, 59 : 372 - 372
[9] Distance and Load Insensitive Inductive Powering for Implantable Medical Devices Through Wireless Communication
Zhu, Guijie
Mai, Songping
Zhang, Chun
Wang, Zhihua
[J]. 2017 IEEE WIRELESS POWER TRANSFER CONFERENCE (WPTC 2017), 2017,
[10] Wireless Intra-Brain Communication for Image Transmission through Mouse Brain
Sasagawa, Kiyotaka
Matsuda, Takashi
Davis, Peter
Zhang, Bing
Li, Keren
Kobayashi, Takuma
Noda, Toshihiko
Tokuda, Takashi
Ohta, Jun
[J]. 2011 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC), 2011, : 2917 - 2920

← 1 2 3 →