Ras-Pathway Inhibition With Targeted Therapies Abrogates Self-Renewal In Acute Myelogenous Leukemia

被引：0
|
作者：
LaRue, Rebecca S.
Hanh Nguyen
Sachs, Karen
Hassan, Nurul Azyan Mohd
Diaz-Flores, Ernesto
Rathe, Susan K.
Sarver, Aaron G.
Bendall, Sean C.
Ha, Ngoc A.
Diers, Miechaleen D.
Nolan, Garry P.
Shannon, Kevin
Sachs, Zohar
Largaespada, David A.
机构：
来源：
BLOOD | 2013年 / 122卷 / 21期
关键词：
D O I：
10.1182/blood.V122.21.819.819
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
819
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Chronic versus acute myelogenous leukemia:: A question of self-renewal
    Jamieson, CHM
    Weissman, IL
    Passegué, E
    [J]. CANCER CELL, 2004, 6 (06) : 531 - 533
  • [2] NRASG12V oncogene mediates self-renewal in a murine model of acute myelogenous leukemia
    Sachs, Zohar
    LaRue, Rebecca S.
    Nguyen, Hanh T.
    Sachs, Karen
    Hassan, Nurul Azyan Mohd
    Diaz-Flores, Ernesto
    Rathe, Susan K.
    Sarver, Aaron L.
    Bendall, Sean C.
    Ha, Ngoc A.
    Diers, Miechaleen D.
    Nolan, Garry P.
    Shannon, Kevin M.
    Largaespada, David A.
    [J]. MOLECULAR CANCER RESEARCH, 2014, 12
  • [3] SELF-RENEWAL INHIBITION OF ACUTE MYELOID-LEUKEMIA CLONOGENIC CELLS BY BIOLOGICAL INDUCERS OF DIFFERENTIATION
    FERRERO, D
    CARLESSO, N
    PREGNO, P
    GALLO, E
    PILERI, A
    [J]. LEUKEMIA, 1992, 6 (02) : 100 - 106
  • [4] NRAS9G12V oncogene facilitates self-renewal in a murine model of acute myelogenous leukemia
    Sachs, Zohar
    LaRue, Rebecca S.
    Nguyen, Hanh T.
    Sachs, Karen
    Noble, Klara E.
    Hassan, Nurul Azyan Mohd
    Diaz-Flores, Ernesto
    Rathe, Susan K.
    Sarver, Aaron L.
    Bendall, Sean C.
    Ha, Ngoc A.
    Diers, Miechaleen D.
    Nolan, Garry P.
    Shannon, Kevin M.
    Largaespada, David A.
    [J]. BLOOD, 2014, 124 (22) : 3274 - 3283
  • [5] Is myelodysplastic related acute myelogenous leukemia a distinct entity from de novo acute myelogenous leukemia? Potential for targeted therapies
    Rosenfeld, C
    Kantarjian, H
    [J]. LEUKEMIA & LYMPHOMA, 2001, 41 (5-6) : 493 - 500
  • [6] INHIBITION OF CDC42 GTPASE MOBILIZES ACUTE MYELOID LEUKEMIA AND IMPAIRS LEUKEMIA STEM CELL SELF-RENEWAL
    Mizukawa, Benjamin
    O'Brien, Eric
    Liu, Wei
    Wunderlich, Mark
    Zheng, Yi
    Mulloy, James
    [J]. PEDIATRIC BLOOD & CANCER, 2013, 60 : S3 - S4
  • [7] Inhibition of pentose phosphate pathway suppresses acute myelogenous leukemia
    Chen, Yan
    Xu, Qian
    Ji, Dexiang
    Wei, Yanlin
    Chen, Huamei
    Li, Tingting
    Wan, Bolin
    Yuan, Liya
    Huang, Ruibin
    Chen, Guoan
    [J]. TUMOR BIOLOGY, 2016, 37 (05) : 6027 - 6034
  • [8] Activation of the RAS pathway is predictive for a chemosensitive phenotype of acute myelogenous leukemia blasts
    Illmer, T
    Thiede, C
    Fredersdorf, A
    Stadler, S
    Neubauer, A
    Ehninger, G
    Schaich, M
    [J]. CLINICAL CANCER RESEARCH, 2005, 11 (09) : 3217 - 3224
  • [9] Self-Renewal of Acute Lymphocytic Leukemia Cells Is Limited by the Hedgehog Pathway Inhibitors Cyclopamine and IPI-926
    Lin, Tara L.
    Wang, Qiuju H.
    Brown, Patrick
    Peacock, Craig
    Merchant, Akil A.
    Brennan, Sarah
    Jones, Evan
    McGovern, Karen
    Watkins, D. Neil
    Sakamoto, Kathleen M.
    Matsui, William
    [J]. PLOS ONE, 2010, 5 (12):
  • [10] Self-renewal of acute lymphocytic leukemia cells is limited by the Hedgehog pathway inhibitors cyclopamine and IPI-926
    Lin, Tara
    Wang, Qiuju
    Brown, Patrick
    Peacock, Craig
    Brennan, Sarah
    Merchant, Akil
    Jones, Evan
    McGovern, Karen
    Watkins, D.
    Sakamoto, Kathleen
    Matsui, William
    [J]. CANCER RESEARCH, 2008, 68 (09)
12345