Synthesis of orthogonally protected lanthionines:: a reassessment of the use of alanyl β-cation equivalents

被引：0
|
作者：
Mustapa, MFM
Harris, R
Mould, J
Chubb, NAL
Schultz, D
Driscoll, PC
Tabor, AB
机构：
[1] UCL, Christopher Ingold Labs, Dept Chem, London WC1H OAJ, England
[2] UCL, Dept Biochem & Mol Biol, Bloomsbury Ctr Struct Biol, London WC1E 6BT, England
[3] Pfizer Ltd, Sandwich CT13 9NJ, Kent, England
[4] Ludwig Inst Canc Res, London W1W 7BS, England
来源：
TETRAHEDRON LETTERS | 2002年 / 43卷 / 46期
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D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Whilst developing a strategy for the solid-phase synthesis of lanthionine-containing peptides, we became aware of sonic problems with a previously published route for the synthesis of orthogonally-protected lanthionine. We report a structural reassignment of the key iodoalanine intermediate and resulting lanthionine derivatives. (C) 2002 Elsevier Science Ltd. All rights reserved.
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页码：8359 / 8362
页数：4
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