Utility of Anakinra in Acute Crystalline Diseases: A Retrospective Study Comparing a University Hospital with a Veterans Affairs Medical Center

被引：12

作者：

Desmarais, Julianna ^{[1
]}

Chu, Cong-Qiu ^{[1
,2
]}

机构：

[1] Oregon Hlth & Sci Univ, Div Arthrit & Rheumat Dis, Portland, OR 97201 USA

[2] VA Portland Hlth Care System, Rheumatol Sect, Portland, OR USA

来源：

JOURNAL OF RHEUMATOLOGY | 2019年 / 46卷 / 07期

关键词：

GOUT; PSEUDOGOUT; ANAKINRA; GOUT; ARTHRITIS; EFFICACY;

D O I：

10.3899/jrheum.180393

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective. To evaluate the efficacy and safety of anakinra in inpatient management of acute gout and pseudogout. Methods. Hospitalized patients with acute gout (n = 77) or pseudogout (n = 11) or both (n = 3) were analyzed for response to anakinra and adverse effects. Results. Half of all patients had comorbidities limiting the treatment choice. Anakinra was well tolerated, and 92% of gout flares and 79% of pseudogout flares responded to treatment. Conclusion. Anakinra is an effective and safe treatment for acute gout and pseudogout in hospitalized patients, particularly in those with comorbidities.

引用

页码：748 / 750

页数：3

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