Should central venous catheters be rapidly removed to treat Staphylococcus aureus related-catheter bloodstream infection (CR-BSI) in neonates and children? An 8-year period (2010-2017) retrospective analysis in a French University Hospital

被引：3

作者：

Boussamet, L. ^{[1
]}

Launay, E. ^{[2
]}

Thomas, E. ^{[3
]}

Leguen, C. Gras ^{[2
]}

Lepelletier, D. ^{[1
,3
]}

机构：

[1] Univ Nantes, MiHAR Lab, FR-44000 Nantes, France

[2] Nantes Univ Hosp, Pediat Dept, FR-44000 Nantes, France

[3] Nantes Univ Hosp, Bacteriol & Infect Control Dept, FR-44000 Nantes, France

来源：

JOURNAL OF HOSPITAL INFECTION | 2019年 / 103卷 / 01期

关键词：

Catheter-related bloodstream infection; Central venous catheters; Neonates; Children; Rapid catheter removal; BACTEREMIA;

D O I：

10.1016/j.jhin.2019.03.015

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Catheter-related bloodstream infection (CR-BSI) treatment is based on empiric anti-biotherapy associated with or without catheter removal. The aim of this study was to compare the incidence of failures in neonates and children with Staphylococcus aureus CR-BSI with or without rapid catheter removal. Treatment failure was defined as the persistence of positive blood cultures, onset or aggravation of a local or systemic complication, or relapse. Fifty-four CR-BSI in 225 patients were analysed (33 and 21 conservative and non-conservative treatments) with three and 10 failures, respectively (P<0.002). Non-conservative treatment with rapid catheter removal seems to be associated with a significantly lower failure rate and should be recommended. (C) 2019 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

引用

页码：97 / 100

页数：4