The raise of SBA-SO3H catalytic activity by inducing ultrasound irradiation in the multicomponent syntheses

This work shows that ultrasound irradiations and mesoporous SBA-SO3H together can have a synergic effect on the catalysis of highly substituted imidazole, dihydropyrimidinone and dihydropyridine derivatives syntheses via multicomponent coupling method. In this paper, we have presented a system which is combination of mesoporous nanoreactors and ultrasonic irradiation for efficient synthesis of the biologically interesting heterocycles. Induction of ultrasonication on SBA-SO3H has led to a remarkable acceleration on the mass transfer through the mesochannels (or nanoreactors). This modification on the mesochannels caused to development of mild conditions, high selectivity and tolerance with various functional groups and high yields in short reaction time.