Meta-analysis of the Risk Factors of Thrombosis in the Perioperative Period of the Orthopedics Spinal Surgery

To explore the specific risk factors of thrombosis in the perioperative period of orthopedics spinal surgery, a search was conducted with specific keywords in PubMed, EMbase, the Cochrane Library, China National Knowledge Infrastructure, WanFang Data, very important paper and Web of Science databases between January 2015 and December 2019. Two researchers independently screened the literature, extracted the data and cross-checked. RevMan 5.3 software was used for meta-analysis. A total of 6 articles were included in this study, with a total of 23 106 patients. The results of meta-analysis showed that the age standard mean difference (=0.39, 95 % confidence intervals 0.18, 0.59, p=0.0002), blood loss (mean difference =35.26, 95 % confidence intervals 30.18, 40.34, p=0.00001), and operation time (mean difference =13.49, 95 % confidence intervals 5.34, 21.64, p=0.001) of the experimental group were significantly higher than those of the control group, and the body mass index mean difference was -1.82, 95 % confidence intervals (-2.79, -0.85, p=0.0002) of the experimental group was significantly lower than that of the control group. There was no significant difference in the number of female (odds ration=2.23, 95 % confidence intervals 0.65, 7.69, p=0.2) and male (odds ration=0.65, 95 % confidence intervals CI 0.32, 1.32, p=0.23) patients between the experimental group and the control group. Age, operation time, blood loss, and body mass index were the risk factors of thrombosis in the perioperative period of orthopedics spinal surgery.