SYNTHESIS OF 3-(3-METHYL-1-ARYL-1H-PYRAZOL-5-YL)-2H-2-CHROMEN-2-ONE DERIVATIVES VIA A ONE-POT, THREE-COMPONENT REACTION

被引：8
|
作者：
Alizadeh, Abdolali [1 ]
Ghanbaripour, Rashid [1 ]
机构：
[1] Tarbiat Modares Univ, Dept Chem, Tehran, Iran
来源：
SYNTHETIC COMMUNICATIONS | 2014年 / 44卷 / 11期
关键词：
Arylhydrazine; coumarin; 4-hydroxy-6-methyl-2H-pyran-2-one; pyrazole; salicylaldehyde; COUMARIN DERIVATIVES; BINDING-SITE; INHIBITORS; COMPLEXES; CATALYST; PYRAZOLE; LIGANDS;
D O I：
10.1080/00397911.2013.867507
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient synthesis of 3-(3-methyl-1-aryl-1H-pyrazol-5-yl)-2H-2-chromen-2-one derivatives by the reaction of salicylaldehydes, 4-hydroxy-6-methyl-2H-pyran-2-one, and arylhydrazine in acetonitrile under reflux condition and in the presence of piperidine is reported. This three-component reaction has some advantages such as ease of handling, good yields, and easy purification. All structures were confirmed by infrared, mass, H-1 NMR, and C-13 NMR spectroscopy.
引用
收藏
页码：1635 / 1640
页数：6
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