Conformational analysis of some C2-symmetric cyclic peptides containing tetrahydrofuran amino acids

被引:17
|
作者
Chakraborty, Tushar Kanti [1 ]
Roy, Saumya [1 ]
Koley, Dipankar [1 ]
Dutta, Samit Kumar [1 ]
Kunwar, Ajit Chand [1 ]
机构
[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India
来源
JOURNAL OF ORGANIC CHEMISTRY | 2006年 / 71卷 / 16期
关键词
D O I
10.1021/jo060470x
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Cyclic oligomers of tetrahydrofuran amino acids, cyclo( Taa1-Leu-Val)(2) ( left), cyclo-( Taa2-Leu-Val)(2) ( middle), and cyclo-( Taa2-Phe-Leu)(2) ( right), displayed well-defined intramolecularly hydrogen-bonded structures with distorted "beta-beta corner" motifs similar to the tennis ball seam.
引用
收藏
页码:6240 / 6243
页数:4
相关论文
共 50 条
  • [1] Synthesis and conformational analysis of linear and cyclic peptides containing sugar amino acids
    vonRoedern, EG
    Lohof, E
    Hessler, G
    Hoffmann, M
    Kessler, H
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (42) : 10156 - 10167
  • [2] C2-symmetric tetrahydrofuran pentamer I
    Koert, U.
    Stein, M.
    Harms, K.
    Angewandte Chemie (International Edition in English), 1994, 33 (11): : 1180 - 1182
  • [3] Chiral discrimination of α-amino acids with a C2-symmetric homoditopic receptor
    Sambasivan, Sunderraman
    Kim, Dae-sik
    Ahn, Kyo Han
    CHEMICAL COMMUNICATIONS, 2010, 46 (04) : 541 - 543
  • [4] Preferential mode of cyclization of tetrahydrofuran amino acids containing peptides: some theoretical insights
    Kumar, N. V. Suresh
    Sharma, Purshotam
    Singh, Harjinder
    Koley, Dipankar
    Roy, Saumya
    Chakraborty, Tushar Kanti
    JOURNAL OF PHYSICAL ORGANIC CHEMISTRY, 2010, 23 (03) : 238 - 245
  • [5] Synthesis, Conformational Analysis and Biological Studies of Cyclic Cationic Antimicrobial Peptides Containing Sugar Amino Acids
    Chakraborty, Tushar Kanti
    Koley, Dipankar
    Ravi, Rapolu
    Krishnakumari, Viswanatha
    Nagaraj, Ramakrishnan
    Kunwar, Ajit Chand
    JOURNAL OF ORGANIC CHEMISTRY, 2008, 73 (22): : 8731 - 8744
  • [6] Conformational properties of hybrid peptides containing α- and ω-amino acids
    Roy, RS
    Balaram, P
    JOURNAL OF PEPTIDE RESEARCH, 2004, 63 (03): : 279 - 289
  • [7] Conformational properties of peptides containing dehydro amino acids
    Thormann, M.
    Hofmann, H.-J.
    Journal of Molecular Structure, 431 (01):
  • [8] Conformational properties of peptides containing dehydro amino acids
    Thormann, M
    Hofmann, HJ
    JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM, 1998, 431 (1-2): : 79 - 96
  • [9] Conformational studies on peptides containing α,α-disubstituted α-amino acids: chiral cyclic α,α-disubstituted α-amino acid as an α-helical inducer
    Demizu, Yosuke
    Doi, Mitsunobu
    Kurihara, Masaaki
    Okuda, Haruhiro
    Nagano, Masanobu
    Suemune, Hiroshi
    Tanaka, Masakazu
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2011, 9 (09) : 3303 - 3312
  • [10] The asymmetric synthesis and conformational analysis of new C2-symmetric macrocycles derived from head-to-head linked α-amino acids and benzene or pyridine
    Bailey, PD
    Everitt, SRL
    Morgan, KM
    Brewster, AG
    TETRAHEDRON, 2001, 57 (07) : 1379 - 1386