The Au(I)-Catalyzed Intramolecular Hydroarylation of Terminal Alkynes Under Mild Conditions: Application to the Synthesis of 2H-Chromenes, Coumarins, Benzofurans, and Dihydroquinolines

被引：152

作者：

Menon, Rajeev S. ^{[1
]}

Findlay, Alison D. ^{[1
]}

Bissember, Alex C. ^{[1
]}

Banwell, Martin G. ^{[1
]}

机构：

[1] Australian Natl Univ, Inst Adv Studies, Res Sch Chem, Canberra, ACT 0200, Australia

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2009年 / 74卷 / 22期

基金：

澳大利亚研究理事会;

关键词：

C-H BONDS; HOMOGENEOUS GOLD CATALYSIS; CYCLOISOMERIZATION REACTION; SIMPLE ARENES; ALKENES; CYCLIZATION; ACTIVATION; COMPLEXES; EFFICIENT; PLATINUM;

D O I：

10.1021/jo902032p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Operationally simple Au(I)-catalyzed intramolecular hydroarylation (IMHA) reactions of terminal alkynes that proceed in high yield and under very mild conditions are described. These processes involve low catalyst loadings., mild reaction temperatures, and short reaction times, require no cocatalysts or additives, and allow for the generation of a number of important heterocyclic motifs from readily accessible starting materials.

引用

页码：8901 / 8903

页数：3

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