First chiral phosphoroamidite-phosphite ligands for highly enantioselective and versatile Pd-catalyzed asymmetric allylic substitution reactions

被引：41
|
作者：
Raluy, Eva [1 ]
Claver, Carmen [1 ]
Pamies, Oscar [1 ]
Dieguez, Montserrat [1 ]
机构：
[1] Univ Rovira & Virgili, Dept Quim Fis & Inorgan, Tarragona 43007, Spain
来源：
ORGANIC LETTERS | 2007年 / 9卷 / 01期
关键词：
D O I：
10.1021/ol0624631
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of phosphite-phosphoroamidite ligands, derived from readily available D-xylose, has been successfully applied for the first time in the Pd-catalyzed allylic substitution of several substrates with different steric and electronic properties, with high enantioselectivities (ee's up to 98) and activities in standard conditions.
引用
收藏
页码：49 / 52
页数：4
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