Complete clinical response of metastatic hepatocellular carcinoma to sorafenib in a patient with hemochromatosis: A case report

被引：41
|
作者：
So, Brian J. [1 ]
Bekaii-Saab, Tanios [1 ]
Bloomston, Mark A. [1 ]
Patel, Tushar [1 ]
机构：
[1] Ohio State Univ, Med Ctr, Columbus, OH 43210 USA
来源：
JOURNAL OF HEMATOLOGY & ONCOLOGY | 2008年 / 1卷 / 1期
关键词：
Renal Cell Carcinoma; Complete Remission; Sorafenib; Gastrointestinal Stromal Tumor; Hemochromatosis;
D O I：
10.1186/1756-8722-1-18
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Hepatocellular carcinoma is rare, but increasing in prevalence in the United States. Recent studies have shown that sorafenib, a multikinase inhibitor, can reduce tumor progression in patients with this cancer. However, complete remission has not been observed. We report a case of a 78-year old patient with unresectable metastatic hepatocellular carcinoma who had a rapid and complete clinical response following therapy with sorafenib for six months. No evidence of disease recurrence has been noted for 6 months after discontinuation of therapy.
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页数：3
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