Muscle Contractile Function and Neural Control after Repetitive Endurance Cycling

ROSS, E. Z., W. GREGSON, K. WILLIAMS, C. ROBERTSON, and K. GEORGE. Muscle Contractile Function and Neural Control after Repetitive Endurance Cycling. Med. Sci. Sports Exerc., Vol. 42, No. 1, pp. 206-212, 2010. Purpose: To examine alterations in muscle contractile properties, cortical excitability, and voluntary activation as a consequence of 20 d of repetitive endurance cycling within a 22-d period. Methods: Eight well-trained male cyclists completed 20 prolonged cycling stages interspersed by two rest days (days 9 and 17). which replicated the 2007 Tour de France route and schedule. Isometric knee extensor torque and EMG responses of the vastus lateralis in response to percutaneous electrical stimulation and transcranial magnetic stimulation were measured before, on days 9 and 17, and 2 d after completion of Tour de France. Postexercise measurements oil days 9 and 17 were taken > 18 h after cessation of the previous exercise bout. Results: Maximal Voluntary contraction of the knee extensors decreased by 20 +/- 10% (P < 0.01) during Tour de France but recovered after 2 d of rest. Peripherally evoked M-wave and potentiated twitch responses were also significantly decreased during Tour de France, up to 31 +/- 21% and 22 +/- 18%, respectively (P < 0.05) but returned to baseline values after 2 d of recovery. Voluntary activation was reduced to 75 +/- 8% (P < 0.05) during Tour de France and remained significantly depressed (79 +/- 7%, P < 0.05) after completion. The amplitude of motor evoked potentials was decreased by 44 +/- 28% (P < 0.01) on day 9 and remained significantly depressed during the remainder of. and after, Tour de France. Conclusions: A reduction ill knee extensor strength, which occurs after repetitive prolonged cycling exercise, is a result of both central and peripheral processes. Reduced sarcoleminal excitability and impairment of contractile mechanisms exists even after 18 h of recovery. An enduring reduction in corticomotor output persists even after 2 d of rest.