Computers have assisted people with disabilities in all phases of life and have helped increase opportunities for them to become more productive members of society. Rehabilitation service providers can offer improved services with greater knowledge of computer assistive technology. This article discusses computer adaptations and alternative input devices (e.g., alternative computer keyboards, switches, mouse modifications, eye-tracking devices), alternative input processing aids (e.g., word prediction, reading and writing aids, electronic reference tools), and alternative output (e.g., motor, visual, auditory, and tactile representation) to facilitate use of computers by persons who have disabilities.