Eltrombopag Promotes DNA Repair in Human Hematopoietic Stem and Progenitor Cells: Implications for the Treatment of Fanconi Anemia

被引:0
|
作者
Guenther, Kacey Linnea
Cheruku, Patali Shikhi
Smith, Richard H.
Larochelle, Andre
机构
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
776
引用
收藏
页数:3
相关论文
共 50 条
  • [1] Eltrombopag promotes DNA repair in human hematopoietic stem and progenitor cells
    Guenther, Kacey L.
    Cheruku, Patali S.
    Cash, Ayla
    Smith, Richard H.
    Alvarado, Luigi J.
    Burkett, Sandra
    Townsley, Danielle M.
    Winkler, Thomas
    Larochelle, Andre
    [J]. EXPERIMENTAL HEMATOLOGY, 2019, 73 : 1 - 6
  • [2] The Thrombopoietin Receptor Agonist Eltrombopag Has DNA Repair Activity in Human Hematopoietic Stem and Progenitor Cells
    Cheruku, Patali S.
    Cash, Ayla
    Dunbar, Cynthia E.
    Young, Neal S.
    Larochelle, Andre
    [J]. BLOOD, 2015, 126 (23)
  • [3] Therapeutic Base and Prime Editing in Fanconi Anemia Hematopoietic Stem and Progenitor Cells
    Ugalde, L.
    Karasu, M. E.
    Olalla, B.
    Siegner, S.
    Garcia, L.
    Clemens, A.
    Alvarez, L.
    Pena, I.
    Bueren, J. A.
    Corn, J. E.
    Rio, P.
    [J]. HUMAN GENE THERAPY, 2022, 33 (23-24) : A62 - A63
  • [4] Human fanconi anemia monoubiquitination pathway promotes homologous DNA repair
    Nakanishi, K
    Yang, YG
    Pierce, AJ
    Taniguchi, T
    Digweed, M
    D'Andrea, AD
    Wang, ZQ
    Jasin, M
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (04) : 1110 - 1115
  • [5] Fanconi Anemia and the Response of Human Hematopoietic Cells to DNA Damage
    Trottier, Magan
    Meyn, Stephen
    [J]. BLOOD, 2008, 112 (11) : 168 - 168
  • [6] Eltrombopag Add-on Treatment in a Child With Fanconi Aplastic Anemia Awaiting Hematopoietic Stem Cell Transplantation
    Aydin Koker, Sultan
    Caliskan Polat, Arzu
    [J]. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2022, 44 (01) : E74 - E76
  • [7] Differential Response of Fanconi Anemia Hematopoietic Stem and Progenitor Cells to Oxidative and Oncogenic Stresses
    Du, Wei
    Amarachintha, Surya
    Ozlem, Erden
    Pang, Qishen
    [J]. BLOOD, 2014, 124 (21)
  • [8] DNA repair capacity of hematopoietic stem and myeloid progenitor cells
    Mohrin, Mary
    Bourke, Emer
    Morrison, Ciaran
    Passegue, Emmanuelle
    [J]. EXPERIMENTAL HEMATOLOGY, 2008, 36 (07) : S4 - S4
  • [9] mTOR Regulates DNA Damage Response of Hematopoietic Stem and Progenitor Cells Through Modulation of Fanconi Anemia Core Complex
    Guo, Fukun
    Li, Jie
    Du, Wei
    Zhang, Shuangmin
    Liu, Wei
    Thomas, George
    Kozma, Sara
    Pang, Qishen
    Zheng, Yi
    [J]. BLOOD, 2011, 118 (21) : 394 - 394
  • [10] Adenine base editing efficiently restores the function of Fanconi anemia hematopoietic stem and progenitor cells
    Siegner, Sebastian M.
    Ugalde, Laura
    Clemens, Alexandra
    Garcia-Garcia, Laura
    Bueren, Juan A.
    Rio, Paula
    Karasu, Mehmet E.
    Corn, Jacob E.
    [J]. NATURE COMMUNICATIONS, 2022, 13 (01)