Heteropolyacid-silica mediated [3+2] cycloaddition of azomethine ylides - a facile multicomponent one-pot synthesis of novel dispiroheterocycles

被引：52
|
作者：
Babu, A. R. Suresh [1 ]
Raghunathan, R. [1 ]
机构：
[1] Univ Madras, Dept Chem, Madras 600025, Tamil Nadu, India
来源：
TETRAHEDRON LETTERS | 2006年 / 47卷 / 52期
关键词：
D O I：
10.1016/j.tetlet.2006.10.139
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient synthesis of dispiroindenoquinoxaline pyrrolizidine derivatives has been expediently accomplished by a one-pot four component 1,3-dipolar cycloaddition reaction. High regioselectivity was achieved using heteropolyacid H-4[Si(W3O10)(3)]-silica as a catalyst. X-ray diffraction studies of one of the cycloadducts proved the structure and regiochemistry of the cycloadduct. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码：9221 / 9225
页数：5
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