Synthesis of novel chiral bisoxazoline ligands with a norbornadiene backbone: use in the copper-catalyzed enantioselective Henry reaction

被引：1

作者：

Delikus, Rabia ^{[1
]}

Cakir, Emine ^{[1
]}

Demirel, Nadir ^{[1
]}

Balci, Metin ^{[2
]}

Karatas, Betul ^{[1
]}

机构：

[1] Ahi Evran Univ, Fac Arts & Sci, Dept Chem, Kirsehir, Turkey

[2] Middle E Tech Univ, Dept Chem, Fac Arts & Sci, TR-06531 Ankara, Turkey

来源：

TURKISH JOURNAL OF CHEMISTRY | 2016年 / 40卷 / 02期

关键词：

Asymmetric synthesis; Henry reaction; chiral bisoxazolines; nitroaldol; copper; SCHIFF-BASE LIGANDS; ASYMMETRIC HENRY; NITROALDOL REACTION; AMINO-ALCOHOLS; COMPLEXES; BIS(OXAZOLINE); EFFICIENT; ACTIVATION;

D O I：

10.3906/kim-1504-80

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Novel chiral bisoxazoline ligands based on norbornadiene were synthesized and used for the asymmetric Henry reaction. Various aromatic aldehydes were converted into chiral beta-nitro alcohols with high yields and moderate to acceptable enantioselectivities under the optimized reaction conditions.

引用

页码：248 / 261

页数：14

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